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Literature summary for 3.1.2.6 extracted from
- Purification and characterisation of glyoxalase II from human red blood cells (1993), Eur. J. Biochem., 213, 1261-1267.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| S-p-nitrobenzyloxycarbonylglutathione | potent competitive | Homo sapiens |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0218 | - |
S-D-mandeloylglutathione | - |
Homo sapiens | |
| 0.0966 | - |
S-L-glyceroylglutathione | - |
Homo sapiens | |
| 0.146 | - |
S-D-lactoylglutathione | - |
Homo sapiens | |
| 0.237 | - |
S-glycolylglutathione | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29200 | - |
1 * 29200, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2007 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactoylglutathione + H2O | S-D-lactoylglutathione | Homo sapiens | D-lactate + glutathione | - |
? | |
| S-D-mandeloylglutathione + H2O | - |
Homo sapiens | D-mandelate + glutathione | - |
? | |
| S-glycerylglutathione + H2O | - |
Homo sapiens | glycerate + glutathione | - |
? | |
| S-glycoloylglutathione + H2O | - |
Homo sapiens | glycolate + glutathione | - |
? | |
| S-L-glyceroylglutathione + H2O | - |
Homo sapiens | glycerate + glutathione | - |
? | |
| S-mandeloylglutathione + H2O | - |
Homo sapiens | mandelate + glutathione | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 29200, SDS-PAGE | Homo sapiens |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 183 | - |
S-D-mandeloylglutathione | - |
Homo sapiens | |
| 727 | - |
S-D-lactoylglutathione | - |
Homo sapiens | |
| 1490 | - |
S-L-glyceroylglutathione | - |
Homo sapiens | |
| 1740 | - |
S-glycoloylglutathione | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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