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Literature summary for 3.1.2.6 extracted from

  • Talesa, V.; Uotila, L.; Koivusalo, M.; Principato, G.; Giovannini, E.; Rosi, G.
    Demonstration of glyoxalase II in rat liver mitochondria. Partial purification and occurrence in multiple forms (1988), Biochim. Biophys. Acta, 955, 103-110.
    View publication on PubMed
Search for more literature for 3.1.2.6

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.044
-
 S-(beta-ethoxy-alpha-D-hydroxybutyryl)glutathione cytosolic enzyme Rattus norvegicus
0.05
-
 S-(beta-ethoxy-alpha-D-hydroxybutyryl)glutathione mitochondrial enzyme Rattus norvegicus
0.16
-
 S-succinylglutathione mitochondrial enzyme Rattus norvegicus
0.213
-
 S-formylglutathione cytosolic enzyme Rattus norvegicus
0.214
-
 S-propionylglutathione cytosolic enzyme Rattus norvegicus
0.242
-
 S-propionylglutathione mitochondrial enzyme Rattus norvegicus
0.325
-
 S-succinylglutathione cytosolic enzyme Rattus norvegicus
0.378
-
 S-propionylglutathione mitochondrial enzyme Rattus norvegicus
0.433
-
 S-D-lactoylglutathione cytosolic enzyme Rattus norvegicus
0.44
-
 S-D-lactoylglutathione mitochondrial enzyme Rattus norvegicus
0.568
-
 S-acetylglutathione cytosolic enzyme Rattus norvegicus
0.662
-
 S-acetylglutathione mitochondrial enzyme Rattus norvegicus
0.703
-
 S-(beta-ethoxy-alpha-D-hydroxybutyryl)glutathione mitochondrial enzyme Rattus norvegicus
0.841
-
 S-Acetoacetylglutathione cytosolic enzyme Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
mitochondrion 10-15% of the total glyoxalase II activity in liver. 56% of the activity resides in the matrix, 19% in the intermembrane space. 3 isoforms are exclusively mitochondrial Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
21000
-
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial, multiple forms Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
112
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lactoylglutathione + H2O
-
 Rattus norvegicus D-lactate + glutathione
-
 ?
S-(beta-ethoxy-alpha-D-hydroxybutyryl)glutathione + H2O
-
 Rattus norvegicus beta-ethoxy-alpha-D-hydroxybutyrate + glutathione
-
 ?
S-acetoacetylglutathione + H2O
-
 Rattus norvegicus acetoacetate + glutathione
-
 ?
S-acetylglutathione + H2O
-
 Rattus norvegicus acetate + glutathione
-
 ?
S-D-lactoylglutathione + H2O
-
 Rattus norvegicus D-lactate + glutathione
-
 ?
S-formylglutathione + H2O
-
 Rattus norvegicus formate + glutathione
-
 ?
S-propionylglutathione + H2O
-
 Rattus norvegicus propionate + glutathione
-
 ?
S-succinylglutathione + H2O
-
 Rattus norvegicus succinate + glutathione
-
 ?