Cloned (Comment) | Organism |
---|---|
expressed as a recombinant His-fusion protein | Synechocystis sp. |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
15478 | - |
x * 15478, calculated from sequence | Synechocystis sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,4-dihydroxy-2-naphthoyl-CoA + H2O | Synechocystis sp. | the reaction is involved in phylloquinone (vitamin K1) biosynthesis | CoA + 1,4-dihydroxy-2-naphthoate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Synechocystis sp. | Q55777 | strain PCC 6803 | - |
Purification (Comment) | Organism |
---|---|
- |
Synechocystis sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,4-dihydroxy-2-naphthoyl-CoA + H2O | the reaction is involved in phylloquinone (vitamin K1) biosynthesis | Synechocystis sp. | CoA + 1,4-dihydroxy-2-naphthoate | - |
? | |
1,4-dihydroxy-2-naphthoyl-CoA + H2O | the enzyme is specific for 1,4-dihydroxy-2-naphthoyl-CoA and displays no activity against benzoyl-CoA, phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA | Synechocystis sp. | CoA + 1,4-dihydroxy-2-naphthoate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 15478, calculated from sequence | Synechocystis sp. |
Synonyms | Comment | Organism |
---|---|---|
DHNA-CoA thioesterase | - |
Synechocystis sp. |
slr0204 | - |
Synechocystis sp. |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Synechocystis sp. |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Synechocystis sp. |
General Information | Comment | Organism |
---|---|---|
malfunction | knockout mutant accumulates 1,4-dihydroxy-2-naphthoyl-CoA, contains 13fold less phylloquinone than the wild-type and displays typical photosensitivity to high light intensities associated with phylloquinone deficiency in cyanobacteria | Synechocystis sp. |
physiological function | the reaction is involved in phylloquinone (vitamin K1) biosynthesis | Synechocystis sp. |