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Literature summary for 3.1.2.22 extracted from
- The antiproliferative agent didemnin B uncompetitively inhibits palmitoyl protein thioesterase (1998), Biochemistry, 37, 10488-10492.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| baculovirally expressed | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Didemnin B | - |
Homo sapiens |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.091 | - |
myristoyl-CoA | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myristoyl-CoA + H2O | - |
Homo sapiens | myristate + CoA | - |
? | |
| palmitoyl-H-Ras + H2O | - |
Homo sapiens | palmitate + Ha-Ras | - |
? | |
| palmitoyl-[protein] + H2O | - |
Homo sapiens | palmitate + protein | - |
? | |
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