Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | strongly decreased levels of ACOT7 activity and protein in cytosol in patients diagnosed with fatty acid oxidation defects | Mus musculus | 5829 | - |
mitochondrion | strongly decreased levels of ACOT7 activity and protein in mitochondria in patients diagnosed with fatty acid oxidation defects | Mus musculus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
SV/129 male and female mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | brown and white, weak expression of Acot7 in male mice | Mus musculus | - |
brain | Acot7 is expressed mainly in brain and testis of male mice. In female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary | Mus musculus | - |
heart | moderate expression in male mice. In female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary | Mus musculus | - |
kidney | weak expression of Acot7 in male mice | Mus musculus | - |
liver | weak expression of Acot7 in male mice | Mus musculus | - |
lung | moderate expression in male mice. In female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary | Mus musculus | - |
additional information | Acot7 gene is expressed as multiple isoforms in a tissue-specific manner. Expression in tissues other than brain and testis is likely to play important roles in fatty acid metabolism. Identification of five possible first exons in mouse Acot7 (Acot7ae). All five first exons are transcribed in a tissue-specific manner | Mus musculus | - |
muscle | weak expression of Acot7 in male mice | Mus musculus | - |
ovary | in female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary | Mus musculus | - |
spleen | weak expression of Acot7 in male mice | Mus musculus | - |
testis | Acot7 is expressed mainly in brain and testis of male mice | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
Acot7 | - |
Mus musculus |
acyl-CoA thioesterase 7 | - |
Mus musculus |
brain acyl-CoA hydrolase | - |
Mus musculus |
CTE-II | - |
Mus musculus |
CTE-IIa | - |
Mus musculus |
long chain acyl-CoA thioester hydrolase | - |
Mus musculus |