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Literature summary for 3.1.2.2 extracted from

  • Sakuma, S.; Fujimoto, Y.; Sawada, T.; Saeki, K.; Akimoto, M.; Fujita, T.
    Existence of acyl-CoA hydrolase-mediated pathway supplying arachidonic acid for prostaglandin synthesis in microsomes from rabbit kidney medulla (1999), Prostaglandins, 57, 63-72.
    View publication on PubMed
Search for more literature for 3.1.2.2

Inhibitors

Inhibitors Comment Organism Structure
lysophosphatidylcholine
-
 Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Oryctolagus cuniculus 5829
-
microsome
-
 Oryctolagus cuniculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
arachidonoyl-CoA + H2O Oryctolagus cuniculus enzyme provides arachidonic acid for prostaglandin synthesis in microsomes of kidney medulla CoA + arachidonate
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney medulla Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.16
-
 kidney cortex microsomes, substrate palmitoyl-CoA Oryctolagus cuniculus
0.21
-
 kidney cortex microsomes, substrate arachidonoyl-CoA Oryctolagus cuniculus
0.26
-
 kidney medulla microsomes, substrate palmitoyl-CoA Oryctolagus cuniculus
0.28
-
 kidney cortex cytosol, substrate palmitoyl-CoA Oryctolagus cuniculus
0.35
-
 kidney medulla microsomes, substrate arachidonoyl-CoA Oryctolagus cuniculus
0.46
-
 kidney medulla cytosol, substrate palmitoyl-CoA Oryctolagus cuniculus
0.47
-
 kidney cortex cytosol, substrate arachidonoyl-CoA Oryctolagus cuniculus
0.54
-
 kidney medulla cytosol, substrate arachidonoyl-CoA Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonoyl-CoA + H2O
-
 Oryctolagus cuniculus CoA + arachidonate
-
 ?
arachidonoyl-CoA + H2O enzyme provides arachidonic acid for prostaglandin synthesis in microsomes of kidney medulla Oryctolagus cuniculus CoA + arachidonate
-
 ?
palmitoyl-CoA + H2O
-
 Oryctolagus cuniculus CoA + palmitate
-
 ?

Synonyms

Synonyms Comment Organism
acyl-CoA hydrolase
-
 Oryctolagus cuniculus
acyl-coenzyme A hydrolase
-
 Oryctolagus cuniculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Oryctolagus cuniculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Oryctolagus cuniculus