Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | - |
Rattus norvegicus | |
Triton X-100 | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Rattus norvegicus | |
KCl | - |
Rattus norvegicus | |
Mg2+ | 0.5 mM gives 40% inhibition | Rattus norvegicus | |
Mn2+ | 0.2 mM gives 60% inhibition | Rattus norvegicus | |
N-ethylmaleimide | 0.001 mM gives 50% inhibition | Rattus norvegicus | |
NaCl | - |
Rattus norvegicus | |
p-hydroxymercuribenzoate | 0.005 mM gives 50% inhibition | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0001 | - |
hexadecanoyl-CoA | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
x * 35000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + H2O | Rattus norvegicus | - |
CoA + palmitate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Renatured (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.15 | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C over 1 month | Rattus norvegicus |
-80°C for several months without notable loss of activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + H2O | long-chain fatty-acyl-CoA | Rattus norvegicus | CoA + a carboxylate | - |
? | |
dodecanoyl-CoA + H2O | i.e. lauroyl-CoA | Rattus norvegicus | CoA + dodecanoate | - |
? | |
hexadecanoyl-CoA + H2O | best substrate | Rattus norvegicus | CoA + hexadecanoate | - |
? | |
hexadecanoyl-CoA + H2O | i.e. palmitoyl-CoA | Rattus norvegicus | CoA + hexadecanoate | - |
? | |
octadecanoyl-CoA + H2O | i.e. stearoyl-CoA | Rattus norvegicus | CoA + octadecanoate | - |
? | |
oleoyl-CoA + H2O | - |
Rattus norvegicus | CoA + oleate | - |
? | |
palmitoyl-CoA + H2O | - |
Rattus norvegicus | CoA + palmitate | - |
? | |
tetradecanoyl-CoA + H2O | i.e. myristoyl-CoA | Rattus norvegicus | CoA + tetradecanoate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 35000, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.9 | - |
- |
Rattus norvegicus |
7.5 | 8 | - |
Rattus norvegicus |
7.8 | 8.2 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.8 | 8.2 | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
N-ethylmaleimide | - |
Rattus norvegicus |