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Literature summary for 3.1.13.2 extracted from
- Mechanism analysis indicates that recombination events in HIV-1 initiate and complete over short distances, explaining why recombination frequencies are similar in different sections of the genome (2009), J. Mol. Biol., 388, 30-47.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E478Q | mutant lacks RNase H function | Human immunodeficiency virus 1 |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Human immunodeficiency virus 1 | using specially designed RNA and DNA transfer substrates in vitro to determine how individual invasion sites contribute to the invasion-mediated mechanism of strand transfer, with specific focus on the limits and influences on the apparently crucial intermediate step of hybrid propagation. Investigation of the roles of the RNase H activities of reverse transcriptase and the strand-exchange properties of nucleocapsid protein (NC) | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | using specially designed RNA and DNA transfer substrates in vitro to determine how individual invasion sites contribute to the invasion-mediated mechanism of strand transfer, with specific focus on the limits and influences on the apparently crucial intermediate step of hybrid propagation. Investigation of the roles of the RNase H activities of reverse transcriptase and the strand-exchange properties of nucleocapsid protein (NC) | Human immunodeficiency virus 1 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| reverse transcriptase ribonuclease H | - |
Human immunodeficiency virus 1 |
| RNase H | - |
Human immunodeficiency virus 1 |
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Release 2023.1 (January 2023)
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