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Literature summary for 3.1.13.2 extracted from

  • Verma, I.M.
    Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H (1975), J. Virol., 15, 843-854.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.13.2

Cloned(Commentary)

Cloned (Comment) Organism
-
 Moloney murine leukemia virus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ optimum: 2 mM for degradation of poly(A)-poly(dT), optimum: 1-2 mM for degradation of X174-DNA-RNA hybrid Moloney murine leukemia virus
Mn2+ optimum: 2 mM for degradation of poly(A)-poly(dT), optimum: 0.1-1.0 mM for degradation of X174DNA-RNA hybrid Moloney murine leukemia virus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
80000
-
 PAGE, sedimentation on glycerol gradients Moloney murine leukemia virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA-RNA hybrid duplex + H2O Moloney murine leukemia virus
-
 oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?
DNA-RNA hybrid duplex + H2O Moloney murine leukemia virus M-MuLV
-
 oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?

Organism

Organism UniProt Comment Textmining
Moloney murine leukemia virus
-
 M-MuLV
-
Moloney murine leukemia virus M-MuLV
-
 M-MuLV
-
More
-
 retrovirus: RNaseH and transcriptase are present in a single polypeptide
-

Purification (Commentary)

Purification (Comment) Organism
-
 Moloney murine leukemia virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA-RNA hybrid duplex + H2O
-
 Moloney murine leukemia virus oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?
DNA-RNA hybrid duplex + H2O
-
 Moloney murine leukemia virus oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety 4-30 nucleotides in length ?
DNA-RNA hybrid duplex + H2O
-
 Moloney murine leukemia virus M-MuLV oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?
DNA-RNA hybrid duplex + H2O
-
 Moloney murine leukemia virus M-MuLV oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety 4-30 nucleotides in length ?
additional information not: ss DNA Moloney murine leukemia virus ?
-
 ?
additional information not: ss RNA Moloney murine leukemia virus ?
-
 ?
additional information not: ds DNA Moloney murine leukemia virus ?
-
 ?
additional information not: ss DNA Moloney murine leukemia virus M-MuLV ?
-
 ?
additional information not: ss RNA Moloney murine leukemia virus M-MuLV ?
-
 ?
additional information not: ds DNA Moloney murine leukemia virus M-MuLV ?
-
 ?