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Literature summary for 3.1.11.5 extracted from

  • Murphy, K.C.
    Biochemical characterization of P22 phage-modified Escherichia coli RecBCD enzyme (1994), J. Biol. Chem., 269, 22507-22516.
    View publication on PubMed
Search for more literature for 3.1.11.5

Inhibitors

Inhibitors Comment Organism Structure
abc protein anti recBCD; binds the recBCD enzyme and inhibits recombination but not exonuclease activity; gamma-protein analog encoded by bacteriophage P22 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Escherichia coli
-
 ADP + phosphate
-
 ?
double-stranded DNA + H2O Escherichia coli ATP-dependent exonuclease single-stranded DNA fragments
-
 ?
double-stranded DNA + H2O Escherichia coli ATP-dependent helicase single-stranded DNA fragments
-
 ?
single stranded DNA + H2O Escherichia coli
-
 5'-phosphomonoester oligonucleotides
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Escherichia coli ADP + phosphate
-
 ?
double-stranded DNA no recombination in recB2109CD mutants and abc-modified recBCD mutants Escherichia coli intermediates with single stranded regions
-
 ?
double-stranded DNA reduced unwinding activity in abc-modified recBCD protein Escherichia coli intermediates with single stranded regions
-
 ?
double-stranded DNA + H2O reduced activity in abc-modified recBCD protein Escherichia coli single-stranded DNA fragments
-
 ?
double-stranded DNA + H2O ATP-dependent exonuclease Escherichia coli single-stranded DNA fragments
-
 ?
double-stranded DNA + H2O ATP-dependent helicase Escherichia coli single-stranded DNA fragments
-
 ?
single stranded DNA + H2O
-
 Escherichia coli 5'-phosphomonoester oligonucleotides
-
 ?