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Literature summary for 3.1.11.2 extracted from

  • Pierce, J.R.; Nazimiec, M.; Tang, M.s.
    Comparison of sequence preference of tomaymycin- and anthramycin-DNA bonding by exonuclease III and lambda exonuclease digestion and UvrABC nuclease incision analysis (1993), Biochemistry, 32, 7069-7078.
    View publication on PubMed

Application

Application Comment Organism
analysis identification of DNA bonding sites of two pyrrolobenzodiazepine derivatives - tomamycin and anthramycin Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded DNA + H2O the enzyme stalls 4-5 bases 3' to DNA bonding site of the two pyrrolobenzodiazepine derivatives - tomamycin and anthramycin Escherichia coli additional information
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