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Literature summary for 3.1.11.2 extracted from

  • Ostermeier, M.; Nixon, A.E.; Benkovic, S.J.
    Incremental truncation as a strategy in the engineering of novel biocatalysts (1999), Bioorg. Med. Chem., 7, 2139-2144.
    View publication on PubMed

Application

Application Comment Organism
analysis the enzyme is used for incremental truncation to create a library of all possible single base-pair deletions of a given piece of DNA. Incremental truncation libraries have application in protein engineering as well as protein folding, enzyme evolution and the chemical synthesis of proteins Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded DNA + H2O
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Escherichia coli additional information
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