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Literature summary for 3.1.1.97 extracted from

  • Lin, Z.; Su, X.; Chen, W.; Ci, B.; Zhang, S.; Lin, H.
    Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis (2014), J. Am. Chem. Soc., 136, 6179-6182.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.97

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphthine methyl ester-[translation elongation factor 2] + H2O Saccharomyces cerevisiae
-
 diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O Saccharomyces cerevisiae the enzyme is involved in diphthamide biosynthesis pathway diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O Homo sapiens the enzyme is involved in diphthamide biosynthesis pathway diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O Saccharomyces cerevisiae ATCC 204508
-
 diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O Saccharomyces cerevisiae ATCC 204508 the enzyme is involved in diphthamide biosynthesis pathway diphthine-[translation elongation factor 2] + methanol
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BTV6
-
-
Saccharomyces cerevisiae P38332
-
-
Saccharomyces cerevisiae ATCC 204508 P38332
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphthine methyl ester-[translation elongation factor 2] + H2O
-
 Saccharomyces cerevisiae diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O the enzyme is involved in diphthamide biosynthesis pathway Saccharomyces cerevisiae diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O the enzyme is involved in diphthamide biosynthesis pathway Homo sapiens diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O diphthine methyl ester i.e. 2-[(3S)-3-carboxy methyl ester-3-(trimethylammonio)propyl]-L-histidine Saccharomyces cerevisiae diphthine-[translation elongation factor 2] + methanol diphthine i.e. 2-[(3S)-3-carboxy-3-(trimethylammonio)propyl]-L-histidine ?
diphthine methyl ester-[translation elongation factor 2] + H2O diphthine methyl ester i.e. 2-[(3S)-3-carboxy methyl ester-3-(trimethylammonio)propyl]-L-histidine Homo sapiens diphthine-[translation elongation factor 2] + methanol diphthine i.e. 2-[(3S)-3-carboxy-3-(trimethylammonio)propyl]-L-histidine ?
diphthine methyl ester-[translation elongation factor 2] + H2O
-
 Saccharomyces cerevisiae ATCC 204508 diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O the enzyme is involved in diphthamide biosynthesis pathway Saccharomyces cerevisiae ATCC 204508 diphthine-[translation elongation factor 2] + methanol
-
 ?
diphthine methyl ester-[translation elongation factor 2] + H2O diphthine methyl ester i.e. 2-[(3S)-3-carboxy methyl ester-3-(trimethylammonio)propyl]-L-histidine Saccharomyces cerevisiae ATCC 204508 diphthine-[translation elongation factor 2] + methanol diphthine i.e. 2-[(3S)-3-carboxy-3-(trimethylammonio)propyl]-L-histidine ?

Synonyms

Synonyms Comment Organism
Dph7
-
 Saccharomyces cerevisiae
Dph7
-
 Homo sapiens
WDR85 locus name Homo sapiens
YBR246W locus name Saccharomyces cerevisiae

General Information

General Information Comment Organism
metabolism the enzyme is involved in diphthamide biosynthesis pathway Saccharomyces cerevisiae
metabolism the enzyme is involved in diphthamide biosynthesis pathway Homo sapiens
metabolism the eukaryotic enzyme is part of the biosynthetic pathway of diphthamide Saccharomyces cerevisiae