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Literature summary for 3.1.1.85 extracted from

  • Xue, Q.; Cui, Y.; Zheng, Q.; Zhang, H.
    Molecular dynamics investigations of BioH protein substrate specificity for biotin synthesis (2016), J. Biomol. Struct. Dyn., 34, 1052-1060 .
    View publication on PubMed
Search for more literature for 3.1.1.85

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pimeloyl-[acyl-carrier protein] methyl ester + H2O Shigella flexneri the enzyme of biotin synthesis plays an important role in fatty acid synthesis which assemble the pimelate moiety pimeloyl-[acyl-carrier protein] + methanol
-
 ?
pimeloyl-[acyl-carrier protein] methyl ester + H2O Shigella flexneri serotype 5b, 8401 the enzyme of biotin synthesis plays an important role in fatty acid synthesis which assemble the pimelate moiety pimeloyl-[acyl-carrier protein] + methanol
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 ?

Organism

Organism UniProt Comment Textmining
Shigella flexneri Q83PW0
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-
Shigella flexneri serotype 5b, 8401 Q83PW0
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
azelayl-[acyl-carrier protein] methyl ester + H2O very low rate of hydrolysis. Tthe slower hydrolysis of azelayl substrate is suggested to be associated with the loose of contacts between BioH and ACP, and with the lost electrostatic interactions of two ionic/hydrogen bonding networks at the interface of the two proteins Shigella flexneri azelayl-[acyl-carrier protein] + methanol
-
 ?
azelayl-[acyl-carrier protein] methyl ester + H2O very low rate of hydrolysis. Tthe slower hydrolysis of azelayl substrate is suggested to be associated with the loose of contacts between BioH and ACP, and with the lost electrostatic interactions of two ionic/hydrogen bonding networks at the interface of the two proteins Shigella flexneri serotype 5b, 8401 azelayl-[acyl-carrier protein] + methanol
-
 ?
pimeloyl-[acyl-carrier protein] methyl ester + H2O
-
 Shigella flexneri pimeloyl-[acyl-carrier protein] + methanol
-
 ?
pimeloyl-[acyl-carrier protein] methyl ester + H2O the enzyme of biotin synthesis plays an important role in fatty acid synthesis which assemble the pimelate moiety Shigella flexneri pimeloyl-[acyl-carrier protein] + methanol
-
 ?
pimeloyl-[acyl-carrier protein] methyl ester + H2O
-
 Shigella flexneri serotype 5b, 8401 pimeloyl-[acyl-carrier protein] + methanol
-
 ?
pimeloyl-[acyl-carrier protein] methyl ester + H2O the enzyme of biotin synthesis plays an important role in fatty acid synthesis which assemble the pimelate moiety Shigella flexneri serotype 5b, 8401 pimeloyl-[acyl-carrier protein] + methanol
-
 ?

Synonyms

Synonyms Comment Organism
BioH protein
-
 Shigella flexneri

General Information

General Information Comment Organism
metabolism the enzyme of biotin synthesis plays an important role in fatty acid synthesis which assemble the pimelate moiety Shigella flexneri