Literature summary for 3.1.1.84 extracted from

Brim, R.; Noon, K.; Collins, G.; Stein, A.; Nichols, J.; Narasimhan, D.; Ko, M.; Woods, J.; Sunahara, R.
The fate of bacterial cocaine esterase (CocE): An in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination (2012), J. Pharmacol. Exp. Ther., 340, 83-95.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli B834 (DE3) cells	Rhodococcus sp.

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
65000	-	x * 65000, SDS-PAGE	Rhodococcus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
cocaine + H2O	Rhodococcus sp.	-	ecgonine methyl ester + benzoate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rhodococcus sp.	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Q-Sepharose column chromatography and phenyl Sepharose column chromatography	Rhodococcus sp.

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cocaine + H2O	-	Rhodococcus sp.	ecgonine methyl ester + benzoate	-	?

Subunits

Subunits	Comment	Organism
?	x * 65000, SDS-PAGE	Rhodococcus sp.

Synonyms

Synonyms	Comment	Organism
cocE	-	Rhodococcus sp.

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Release 2023.1 (January 2023)