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Literature summary for 3.1.1.81 extracted from

  • Rajesh, P.S.; Rai, V.R.
    Purification and antibiofilm activity of AHL-lactonase from endophytic Enterobacter aerogenes VT66 (2015), Int. J. Biol. Macromol., 81, 1046-1052 .
    View publication on PubMed

Application

Application Comment Organism
drug development the AHL-lactonase from Enterobacter aerogenes VT66 can be used as antibiofilm therapeutics in Pseudomonas aeruginosa associated biomedical applications Klebsiella aerogenes

Inhibitors

Inhibitors Comment Organism Structure
Ag+ 1 mM, 79% inhibition. 10 mM, 80% inhibition Klebsiella aerogenes

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
SDS-PAGE Klebsiella aerogenes

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-
Klebsiella aerogenes VT66P
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-3-oxododecanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-3-oxododecanoyl-L-homoserine
-
?
N-3-oxododecanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes VT66P N-3-oxododecanoyl-L-homoserine
-
?
N-3-oxohexanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-3-oxohexanoyl-L-homoserine
-
?
N-3-oxohexanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes VT66P N-3-oxohexanoyl-L-homoserine
-
?
N-butyryl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-butyryl-L-homoserine
-
?
N-decanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-decanoyl-L-homoserine
-
?
N-decanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes VT66P N-decanoyl-L-homoserine
-
?
N-dodecanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-dodecanoyl-L-homoserine
-
?
N-hexanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-hexanoyl-L-homoserine
-
?
N-hexanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes VT66P N-hexanoyl-L-homoserine
-
?
N-octanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes N-octanoyl-L-homoserine
-
?
N-octanoyl-L-homoserine lactone + H2O
-
Klebsiella aerogenes VT66P N-octanoyl-L-homoserine
-
?

Synonyms

Synonyms Comment Organism
AHL-lactonase
-
Klebsiella aerogenes

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
30 60 more than 94% of maximal activity between 30°C and 60°C Klebsiella aerogenes

pH Range

pH Minimum pH Maximum Comment Organism
6.5 8 more than 90% of maximal activity when the pH is between 6.5 and 8.0 Klebsiella aerogenes