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Literature summary for 3.1.1.81 extracted from

  • Khan, S.R.; Farrand, S.K.
    The BlcC (AttM) lactonase of Agrobacterium tumefaciens does not quench the quorum-sensing system that regulates Ti plasmid conjugative transfer (2009), J. Bacteriol., 191, 1320-1329.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information BlcC is inducible by pathway intermediates but not by gamma-butyrolactone or entry into stationary phase. Induction of blc results in an 8 to 10fold decrease in levels of extracellular acyl-HSL but in only a twofold decrease in intracellular quormone levels, a measure of the amount of active intracellular TraR Agrobacterium tumefaciens

Cloned(Commentary)

Cloned (Comment) Organism
gene blcC, genetic organization of the blc operon, expression in Escherichia coli strain M15 as His6-tagged enzyme, expression of BlcC results in greatly diminished levels ofaccumulation of the acyl-HSL signal in culture supernatants Agrobacterium tumefaciens

Protein Variants

Protein Variants Comment Organism
additional information induction or mutational derepression of blc as well as a null mutation in blcC have no significant effect on the induction of or continued transfer of pTiC58 from donors in any stage of growth, including stationary phase, overview Agrobacterium tumefaciens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Agrobacterium tumefaciens BlcC does not degrade the acyl-L-homoserine lactone bound by TraR in the quorum quenching system, overview. BlcC does not significantly affect transfer of the Ti plasmid in planta ?
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Organism

Organism UniProt Comment Textmining
Agrobacterium tumefaciens
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strains A6 and C58, gene blcC
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information BlcC does not degrade the acyl-L-homoserine lactone bound by TraR in the quorum quenching system, overview. BlcC does not significantly affect transfer of the Ti plasmid in planta Agrobacterium tumefaciens ?
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additional information BlcC does not degrade the acyl-L-homoserine lactone bound by TraR Agrobacterium tumefaciens ?
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?

Synonyms

Synonyms Comment Organism
AttM
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Agrobacterium tumefaciens
BlcC
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Agrobacterium tumefaciens