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Literature summary for 3.1.1.8 extracted from

  • Wong, K.K.; Ngo, J.C.; Liu, S.; Lin, H.Q.; Hu, C.; Shaw, P.C.; Wan, D.C.
    Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and kinetic analysis (2010), Chem. Biol. Interact., 187, 335-339.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cryptotanshinone uncompetitive inhibitor Homo sapiens
dihydrotanshinone uncompetitive inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P06276
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylthiocholine + H2O
-
Homo sapiens thiocholine + acetate
-
?

Synonyms

Synonyms Comment Organism
BChE
-
Homo sapiens
butyrylcholinesterase
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00551
-
pH and temperature not specified in the publication Homo sapiens dihydrotanshinone
0.00666
-
pH and temperature not specified in the publication Homo sapiens cryptotanshinone