Literature summary for 3.1.1.8 extracted from

Kovarik, Z.; Katalinic, M.; Sinko, G.; Binder, J.; Holas, O.; Jung, Y.; Musilova, L.; Jun, D.; Kuca, K.
Pseudo-catalytic scavenging: Searching for a suitable reactivator of phosphorylated butyrylcholinesterase (2010), Chem. Biol. Interact., 187, 167-171.

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Inhibitors

Inhibitors	Comment	Organism	Structure
paraoxon	-	Homo sapiens
Tabun	the most potent reactivators of tabun-inhibited BChE are 1,1'-(2,2'-oxybis(ethane-2,1-diyl))bis(4-hydroxyiminomethyl pyridinium) bromide and 4-carbamoyl-1-(2-(2-(4-(hydroxyiminomethyl)pyridinium-1-yl)ethoxy)ethyl)pyridinium bromide. Reactivation by these oximes (1 mM) reaches about 50% of control activity after 20 min, however, reactivation stops at 70%	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P06276	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood plasma	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
butyrylthiocholine + H2O	-	Homo sapiens	thiocholine + butyrate	-	?

Synonyms

Synonyms	Comment	Organism
BChE	-	Homo sapiens
butyrylcholinesterase	-	Homo sapiens

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Release 2023.1 (January 2023)