Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.8 extracted from

  • Domenech, C.E.; Garrido, M.N.; Lisa, T.A.
    Pseudomonas aeruginosa cholinesterase and phosphorylcholine phosphatase: two enzymes contributing to corneal infection (1991), FEMS Microbiol. Lett., 66, 131-135.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
butyrylthiocholine competitive Pseudomonas aeruginosa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.13
-
acetylthiocholine
-
Pseudomonas aeruginosa
0.26
-
propionylthiocholine
-
Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pseudomonas aeruginosa enzyme and phosphorylcholine phosphatase coordinately contribute to the breakdown of the corneal epithelial membrane upon infection ?
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
induction by growth on choline, acetylcholine or betaine as sole carbon source
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylthiocholine + H2O
-
Pseudomonas aeruginosa thiocholine + acetate
-
?
additional information enzyme and phosphorylcholine phosphatase coordinately contribute to the breakdown of the corneal epithelial membrane upon infection Pseudomonas aeruginosa ?
-
?
additional information no substrate: butyrylthiocholine Pseudomonas aeruginosa ?
-
?
propionylthiocholine + H2O
-
Pseudomonas aeruginosa thiocholine + propanoate
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.05
-
butyrylthiocholine
-
Pseudomonas aeruginosa