Literature summary for 3.1.1.8 extracted from

Reiner, E.; Simeon-Rudolf, V.; Skrinjaric-Spoljar, M.
Catalytic properties and distribution profiles of paraoxonase and cholinesterase phenotypes in human sera (1995), Toxicol. Lett., 82/83, 447-452.

Search for more literature for 3.1.1.8

Inhibitors

Inhibitors	Comment	Organism	Structure
4,4'-Bipyridine	competitive, reversible	Homo sapiens
HI 6	competitive, reversible	Homo sapiens
additional information	enzyme variants usual, fluoride resistant, and atypical differ in rates of inhibition by the charged organophosphates and carbamates	Homo sapiens
PAM-2	competitive, reversible	Homo sapiens
phosphostigmine	competitive, reversible	Homo sapiens
Ro 02-0683	progressive inhibitor	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.56	-	acetylthiocholine	usual variant	Homo sapiens
0.57	-	propionylthiocholine	atypical variant	Homo sapiens
0.7	-	propionylthiocholine	fluoride resistant variant	Homo sapiens
0.71	-	acetylthiocholine	fluoride resistant variant	Homo sapiens
0.76	-	propionylthiocholine	usual variant	Homo sapiens
0.96	-	acetylthiocholine	atypical variant	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetylthiocholine + H2O	-	Homo sapiens	acetate + thiocholine	-	?
propionylthiocholine + H2O	propylthiocholine	Homo sapiens	propanoate + thiocholine	-	?

Synonyms

Synonyms	Comment	Organism
butyrylcholinesterase	-	Homo sapiens

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Release 2023.1 (January 2023)