Application | Comment | Organism |
---|---|---|
diagnostics | monitoring of enzyme mRNA levels in slit-skin smear specimens from patients with lepromatous and borderline leprosy may be a useful indicator of patient prognosis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macrophage | - |
Homo sapiens | - |
THP-1 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
HSL | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | infection by live Mycobacterium leprae significantly suppresses the enzyme expression levels. This suppression is not observed with dead Mycobacterium leprae or latex bead controls | down |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme expression is abolished in the slit-skin smear specimens from patients with lepromatous and borderline leprosy caused by Mycobacterium leprae, which suppresses lipid degradation through inhibition of enzyme expression | Homo sapiens |
physiological function | key enzyme in fatty acid mobilization and lipolysis | Homo sapiens |