Data extracted from this reference:
Localization
Molecular Weight [Da]
7900
8100
SDS-PAGE of deglycosylated small subunit
Homo sapiens
14000
SDS-PAGE, small subunit
Homo sapiens
52000
SDS-PAGE, large subunit
Homo sapiens
Natural Substrates/ Products (Substrates)
3-(acyloxy)acyl group of bacterial toxin
Homo sapiens
detoxification of LPS
3-hydroxyacyl group of bacterial toxin + a fatty acid
Homo sapiens
Organism
Posttranslational Modification
glycoprotein
glycosylation of the small subunit not essential for activity
Homo sapiens
Purification (Commentary)
Substrates and Products (Substrate)
3-(acyloxy)acyl group of bacterial toxin
detoxification of LPS
246552
Homo sapiens
3-hydroxyacyl group of bacterial toxin + a fatty acid
246552
Homo sapiens
3-(acyloxy)acyl group of bacterial toxin + H2O
246552
Homo sapiens
3-hydroxyacyl group of bacterial toxin + a fatty acid
246552
Homo sapiens
?
Subunits
dimer
1 * 14000 + 1 * 52000, small subunit not required for activity
Homo sapiens
Localization (protein specific)
Molecular Weight [Da] (protein specific)
7900
8100
SDS-PAGE of deglycosylated small subunit
Homo sapiens
14000
SDS-PAGE, small subunit
Homo sapiens
52000
SDS-PAGE, large subunit
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
3-(acyloxy)acyl group of bacterial toxin
Homo sapiens
detoxification of LPS
3-hydroxyacyl group of bacterial toxin + a fatty acid
Homo sapiens
Posttranslational Modification (protein specific)
glycoprotein
glycosylation of the small subunit not essential for activity
Homo sapiens
Purification (Commentary) (protein specific)
Substrates and Products (Substrate) (protein specific)
3-(acyloxy)acyl group of bacterial toxin
detoxification of LPS
246552
Homo sapiens
3-hydroxyacyl group of bacterial toxin + a fatty acid
246552
Homo sapiens
3-(acyloxy)acyl group of bacterial toxin + H2O
246552
Homo sapiens
3-hydroxyacyl group of bacterial toxin + a fatty acid
246552
Homo sapiens
?
Subunits (protein specific)
dimer
1 * 14000 + 1 * 52000, small subunit not required for activity
Homo sapiens
Other publictions for EC 3.1.1.77
749541
Yang
Acyloxyacyl hydrolase modulat ...
Mus musculus
Am. J. Physiol. Regul. Integr. Comp. Physiol.
314
R353-R365
2018
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
751999
Zou
Acyloxyacyl hydrolase promote ...
Mus musculus
PLoS Pathog.
13
e1006436
2017
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
730832
Janelsins
Altered inactivation of commen ...
Mus musculus
Proc. Natl. Acad. Sci. USA
111
373-378
2014
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
5
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
715145
Shao
Prolonged hepatomegaly in mice ...
Mus musculus
Hepatology
54
1051-1062
2011
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
716472
Klaffenbach
Contribution of different plac ...
Homo sapiens
Placenta
32
830-837
2011
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
2
1
1
2
-
-
704964
Ojogun
Overproduction of acyloxyacyl ...
Mus musculus
J. Infect. Dis.
200
1685-1693
2009
-
1
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
1
1
-
-
-
691683
Lu
Host inactivation of bacterial ...
Mus musculus
Cell host microbe
4
293-302
2008
-
-
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
680766
Shao
A host lipase detoxifies bacte ...
Mus musculus
J. Biol. Chem.
282
13726-13735
2007
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
680889
Gioannini
Endotoxin-binding proteins mod ...
Homo sapiens
J. Biol. Chem.
282
7877-7884
2007
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
682968
Mehrzad
Bovine blood neutrophil acylox ...
Bos taurus
Vet. Res.
38
655-668
2007
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
3
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
680332
Barnes
Polymorphisms in the novel gen ...
Homo sapiens
J. Allergy Clin. Immunol.
118
70-77
2006
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
665166
feulner
Identification of acyloxyacyl ...
Mus musculus
Infect. Immun.
72
3171-3178
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
1
-
-
-
7
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
7
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
665875
Lu
Stimulus-dependent deacylation ...
Mus musculus
J. EXp. Med.
197
1745-1754
2003
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246554
Staab
-
Distinctive structural feature ...
Homo sapiens, Mus musculus, Oryctolagus cuniculus
J. Endotoxin Res.
5
205-208
1999
-
-
3
-
-
-
-
3
-
-
-
3
-
3
-
3
-
-
-
-
-
-
6
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
3
-
-
-
3
-
-
3
-
-
-
-
-
6
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246553
Cody
-
Effect of inflammatory and ant ...
Mus musculus
J. Endotoxin Res.
4
371-379
1997
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246552
Staab
A saposin-like domain influenc ...
Homo sapiens
J. Biol. Chem.
269
23736-23742
1994
-
-
-
-
-
-
-
-
1
-
3
1
-
2
-
1
1
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
3
1
-
-
1
1
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246547
Munford
Acyloxyacyl hydrolase, a leuko ...
Homo sapiens
J. Biol. Chem.
267
10116-10121
1992
2
-
-
-
-
-
3
2
-
-
-
1
-
2
-
-
1
-
-
2
-
-
8
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
3
-
2
-
-
-
1
-
-
-
1
-
2
-
-
8
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
246551
Munford
Eukaryotic lipopolysaccharide ...
Homo sapiens
Methods Enzymol.
209
485-492
1992
1
-
1
-
-
-
-
-
-
1
-
1
-
1
-
-
1
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246546
Hagen
Expression and characterizatio ...
Homo sapiens
Biochemistry
30
8415-8423
1991
-
-
1
-
-
-
-
-
-
-
4
1
-
2
-
1
-
-
-
2
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
4
1
-
-
1
-
-
2
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246550
Mc Dermott
-
Intracellular and extracellula ...
Bos taurus, Homo sapiens
Infect. Immun.
59
487-485
1991
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
2
-
-
4
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
4
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
246545
Erwin
Deacylation of structurally di ...
Homo sapiens
J. Biol. Chem.
265
16444-16449
1990
1
1
-
-
-
-
-
3
-
1
-
1
-
8
-
-
1
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
3
-
1
-
1
-
-
-
1
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
246549
Munford
Purification of acyloxyacyl hy ...
Homo sapiens
J. Biol. Chem.
264
15613-15619
1989
1
-
-
-
-
-
1
1
1
-
4
1
-
3
-
1
1
-
-
1
2
-
2
1
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
1
1
-
4
1
-
-
1
1
-
1
2
-
2
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
246548
Munford
Detoxification of bacterial li ...
Homo sapiens
Science
234
203-205
1986
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-