BRENDA - Enzyme Database
show all sequences of 3.1.1.71

Characterization of the enzymatic hydrolysis of acetate from alkylacetylglycerols in the de novo pathway of PAF biosynthesis

Blank, M.L.; Smith, Z.L.; Cress, E.A.; Snyder, F.; Biochim. Biophys. Acta 1042, 153-158 (1990) View publication on PubMed

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
NaF
10 mM
Mus musculus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.045
-
1-Hexadecyl-2-acetyl-sn-glycerol
-
Mus musculus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
10% of total activity
Mus musculus
5829
-
membrane
90% of total activity
Mus musculus
16020
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Mus musculus
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
?
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Mus musculus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
Ehrlich ascites carcinoma cell
-
Mus musculus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1-hexadecyl-2-acetyl-sn-glycerol
-
23590
Mus musculus
1-Hexadecyl-sn-glycerol + acetate
-
23590
Mus musculus
?
2-acetyl-1-alkyl-sn-glycerol
-
23590
Mus musculus
1-Alkyl-sn-glycerol + acetate
-
23590
Mus musculus
?
additional information
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
23590
Mus musculus
?
-
-
-
?
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
NaF
10 mM
Mus musculus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.045
-
1-Hexadecyl-2-acetyl-sn-glycerol
-
Mus musculus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
10% of total activity
Mus musculus
5829
-
membrane
90% of total activity
Mus musculus
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Mus musculus
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
?
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
Ehrlich ascites carcinoma cell
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1-hexadecyl-2-acetyl-sn-glycerol
-
23590
Mus musculus
1-Hexadecyl-sn-glycerol + acetate
-
23590
Mus musculus
?
2-acetyl-1-alkyl-sn-glycerol
-
23590
Mus musculus
1-Alkyl-sn-glycerol + acetate
-
23590
Mus musculus
?
additional information
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
23590
Mus musculus
?
-
-
-
?
Other publictions for EC 3.1.1.71
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
23590
Blank
Characterization of the enzyma ...
Mus musculus
Biochim. Biophys. Acta
1042
153-158
1990
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1
2
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1
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1
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3
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23589
Blank
Conversion of 1-alkyl-2-acetyl ...
Oryctolagus cuniculus
Biochem. Biophys. Res. Commun.
124
156-163
1984
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1
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1
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