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Literature summary for 3.1.1.7 extracted from
- Blocked enzymatic etching of gold nanorods application to colorimetric detection of acetylcholinesterase activity and its inhibitors (2016), ACS Appl. Mater. Interfaces, 8, 11139-11146 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| galantamine | galantamine competes with the substrate for binding to the active site of enzyme AChE in a reversible manner, inhibitory mechanism, overview | Electrophorus electricus |  |
| additional information | thiols block the enzymatic etching of gold nanorods(thiocholine on the rate of horseradish peroxidase-catalyzed AuNR etching), application to colorimetric detection of acetylcholinesterase activity and its inhibitors, method, detailed overview | Electrophorus electricus | |
| paraoxon | - |
Electrophorus electricus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | Michaelis-Menten kinetics | Electrophorus electricus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylcholine + H2O | Electrophorus electricus | - |
choline + acetate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Electrophorus electricus | O42275 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| commercial preparation | - |
Electrophorus electricus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylcholine + H2O | - |
Electrophorus electricus | choline + acetate | - |
? | |
| acetylthiocholine + H2O | - |
Electrophorus electricus | thiocholine + acetate | - |
? | |
| additional information | thiols block the enzymatic etching of gold nanorods(thiocholine on the rate of horseradish peroxidase-catalyzed AuNR etching), application to colorimetric detection of acetylcholinesterase activity and its inhibitors, overview | Electrophorus electricus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acetylcholine esterase | - |
Electrophorus electricus |
| AChE | - |
Electrophorus electricus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
assay at room temperature | Electrophorus electricus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Electrophorus electricus |
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Release 2023.1 (January 2023)
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