Literature summary for 3.1.1.7 extracted from

Xu, Y.; Colletier, J.P.; Jiang, H.; Silman, I.; Sussman, J.L.; Weik, M.
Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design (2008), Protein Sci., 17, 601-605.

Search for more literature for 3.1.1.7

Application

Application	Comment	Organism
drug development	the enzyme is a target for rational drug design	Tetronarce californica

Crystallization (Commentary)

Crystallization (Comment)	Organism
X-ray diffraction crystal structure determination at 1.8 A resolution, crystal structure analysis of ligand-complexed enzyme and of native enzyme side-chain conformations accessed by molecular dynamics simulations, structure comparisons, overview	Tetronarce californica

Organism

Organism	UniProt	Comment	Textmining
Tetronarce californica	P04058	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the catalytic triad is formed by His440, Glu327, and Ser200, Trp84 and Trp279 are important for the enzyme activity	Tetronarce californica	?	-	?

Subunits

Subunits	Comment	Organism
More	crystal structure analysis of ligand-complexed enzyme and of native enzyme side-chain conformations accessed by molecular dynamics simulations, structure comparisons, overview	Tetronarce californica

Synonyms

Synonyms	Comment	Organism
AChE	-	Tetronarce californica

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Release 2023.1 (January 2023)