Literature summary for 3.1.1.7 extracted from

Gholivand, K.; Shariatinia, Z.; Ghadimi, S.; Mojahed, F.; Alizadegan, A.M.; Khajeh, K.; Naderi-Manesh, H.
Acetylcholinesterase inhibition by diaza- and dioxophosphole compounds: synthesis and determination of IC50 values (2004), J. Enzyme Inhib. Med. Chem., 19, 403-407.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-chloro-5-methyl-1,3,2-benzodioxaphosphole 2-oxide	50% inhibition at 0.48 mM, detailed kinetic analysis	Homo sapiens
2-chloro-5-methyl-2,3-dihydro-1H-1,3,2-benzodiazaphosphole 2-oxide	50% inhibition at 1.54 mM, detailed kinetic analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	commercial preparation	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.2	-	2-chloro-5-methyl-1,3,2-benzodioxaphosphole 2-oxide	25°C, pH 7.8	Homo sapiens

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Release 2023.1 (January 2023)