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Literature summary for 3.1.1.7 extracted from

  • Zhan, C.G.; Gao, D.
    Catalytic mechanism and energy barriers for butyrylcholinesterase-catalyzed hydrolysis of cocaine (2005), Biophys. J., 89, 3863-3872.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
amlodipine
-
Electrophorus electricus
amlodipine besylate reversible mixed-type inhibition Electrophorus electricus
chlordiazepoxide HCl reversible mixed-type inhibition Electrophorus electricus
diazepam reversible mixed-type inhibition Electrophorus electricus
hydralazine HCl reversible mixed-type inhibition Electrophorus electricus
lovastatin reversible mixed-type inhibition Electrophorus electricus
nifedipine reversible mixed-type inhibition Electrophorus electricus
simvastatin reversible mixed-type inhibition Electrophorus electricus

Organism

Organism UniProt Comment Textmining
Electrophorus electricus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
Electrophorus electricus
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00019
-
amlodipine
-
Electrophorus electricus
0.0018
-
simvastatin
-
Electrophorus electricus
0.0027
-
lovastatin
-
Electrophorus electricus
0.004
-
nifedipine
-
Electrophorus electricus
0.007
-
hydralazine HCl
-
Electrophorus electricus
0.013
-
diazepam
-
Electrophorus electricus
0.05
-
chlordiazepoxide HCl
-
Electrophorus electricus