Literature summary for 3.1.1.7 extracted from

Ekstrom, F.; Akfur, C.; Tunemalm, A.K.; Lundberg, S.
Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase (2006), Biochemistry, 45, 74-81.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with tabun, prior and after intramolecular dealkylation or deamidation reaction caused by tabun and called aging. Nonaged tabun conjugate induces a structural change at H447 that uncouples the catalytic triad. In aged tabun conjugate, side chains of H447 and F338 are reversed to the conformation of the apo structure of enzyme	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P21836	-	-

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Release 2023.1 (January 2023)