Literature summary for 3.1.1.68 extracted from

Liu, M.; Ding, Y.; Xian, M.; Zhao, G.
Metabolic engineering of a xylose pathway for biotechnological production of glycolate in Escherichia coli (2018), Microb. Cell Fact., 17, 51 .

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Application

Application	Comment	Organism
synthesis	construction of a route for glycolate production in Escherichia coli by introducing NAD+-dependent xylose dehydrogenase xdh and xylonolactonase xylC from Caulobacter crescentus. The engineered strain produces 28.82 g/L glycolate from xylose with 0.60 g/L/h productivity and 0.38 g/g xylose yield. 27.18 g/L acetate accumulates after fermentation. An ackA knockout results in about 66% decrease in acetate formation. The final engineered strain produces 43.60 g/L glycolate, with 0.91 g/L/h productivity and 0.46 g/g xylose yield	Caulobacter vibrioides

Organism

Organism	UniProt	Comment	Textmining
Caulobacter vibrioides	-	-	-
Caulobacter vibrioides NA1000	-	-	-

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Release 2023.1 (January 2023)