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Literature summary for 3.1.1.64 extracted from

  • Amann, P.M.; Luo, C.; Owen, R.W.; Hofmann, C.; Freudenberger, M.; Schadendorf, D.; Eichmueller, S.B.; Bazhin, A.V.
    Vitamin A metabolism in benign and malignant melanocytic skin cells: importance of lecithin/retinol acyltransferase and RPE65 (2012), J. Cell. Physiol., 227, 718-728.
    View publication on PubMed
Search for more literature for 3.1.1.64

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
Ma-Mel-01 cell
-
 Homo sapiens
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Ma-Mel-04 cell
-
 Homo sapiens
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Ma-Mel-05 cell
-
 Homo sapiens
-
Ma-Mel-11 cell
-
 Homo sapiens
-
Ma-Mel-12 cell
-
 Homo sapiens
-
Ma-Mel-17 cell
-
 Homo sapiens
-
Ma-Mel-19 cell
-
 Homo sapiens
-
Ma-Mel-37b cell
-
 Homo sapiens
-
Ma-Mel-42b cell
-
 Homo sapiens
-
Ma-Mel-47 cell
-
 Homo sapiens
-
Ma-Mel-52 cell
-
 Homo sapiens
-
melanoma cell malignant melanoma cells are able to esterify all-trans retinol and subsequently isomerize all-trans retinyl esters into 11-cis retinol, whereas melanocytes are not able to catalyze these reactions Homo sapiens
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MeWo cell
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 Homo sapiens
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additional information melanocytes do not express this enzyme at the protein level Homo sapiens
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SK-MEL-23 cell
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 Homo sapiens
-
UKRV-Mel-06a cell
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 Homo sapiens
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UKRV-Mel-2 cell
-
 Homo sapiens
-
UKRV-Mel-21a cell
-
 Homo sapiens
-
UKRV-Mel-27 cell
-
 Homo sapiens
-
UKRV-Mel-31 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
Rpe65
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function RPE65 is important for vitamin A metabolism in melanoma cells and in keratinocytes. Activity of RPE65 is important for removal of all-trans retinal which is the substrate for retinoic acid production in skin cells Homo sapiens