Cloned (Comment) | Organism |
---|---|
expressed in 293A-lecithin retinol acyltransferase cells | Danio rerio |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bipyridine | the addition of 6 mM FeSO4 into the iron chelator reaction restores partial enzyme activity | Danio rerio |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0026 | - |
an all-trans retinyl ester | pH and temperature not specified in the publication | Danio rerio |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Danio rerio | 5829 | - |
membrane | - |
Danio rerio | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | enzymatic activity is dependent on iron | Danio rerio |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
61000 | - |
x * 61000, estimated from SDS-PAGE | Danio rerio |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | A9C3R9 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA resin column chromatography | Danio rerio |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | 13cIMH expression is detected in the periventricular grey zone of the optic tectum and torus longitudinalis, at the fasciculus longitudinalis medialis in the medulla oblongata, and at the periventricular pretectum | Danio rerio | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
an all-trans retinyl ester + H2O | specific substrate | Danio rerio | 13-cis-retinol + a fatty acid | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 61000, estimated from SDS-PAGE | Danio rerio |
Synonyms | Comment | Organism |
---|---|---|
13-cis isomerohydrolase | - |
Danio rerio |
13cIMH | - |
Danio rerio |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00044 | - |
an all-trans retinyl ester | pH and temperature not specified in the publication | Danio rerio |
General Information | Comment | Organism |
---|---|---|
physiological function | 13cIMH may play a key role in the modulation of neuronal functions in the brain | Danio rerio |