Protein Variants | Comment | Organism |
---|---|---|
F61L | the mutant shows 1.02% activity compared to the wild type enzyme | Homo sapiens |
F61W | the mutant shows 1.28% activity compared to the wild type enzyme | Homo sapiens |
F61Y | the mutant shows 7.57% activity compared to the wild type enzyme | Homo sapiens |
T147A | the mutant shows 12.63% activity compared to the wild type enzyme | Homo sapiens |
T147C | the mutant shows 20.18% activity compared to the wild type enzyme | Homo sapiens |
T147G | the mutant shows 30.02% activity compared to the wild type enzyme | Homo sapiens |
T147S | the mutant shows 84% activity compared to the wild type enzyme | Homo sapiens |
T147V | inactive | Homo sapiens |
T147W | inactive | Homo sapiens |
T147Y | inactive | Homo sapiens |
W331F | the mutant shows 8.34% activity compared to the wild type enzyme | Homo sapiens |
W331L | inactive | Homo sapiens |
W331Q | inactive | Homo sapiens |
W331Y | the mutant shows 26.72% activity compared to the wild type enzyme | Homo sapiens |
Y239C | inactive | Homo sapiens |
Y239D | inactive | Homo sapiens |
Y239F | inactive | Homo sapiens |
Y239L | inactive | Homo sapiens |
Y239S | inactive | Homo sapiens |
Y239T | inactive | Homo sapiens |
Y239W | inactive | Homo sapiens |
Y275F | the mutant shows 14.44% activity compared to the wild type enzyme | Homo sapiens |
Y275I | inactive | Homo sapiens |
Y275W | inactive | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
all-trans-retinyl ester + H2O | - |
Homo sapiens | 11-cis-retinol + a fatty acid | - |
? | |
additional information | RPE65 is not inherently 11-cis-specific and can produce both 11- and 13-cis isomers | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Rpe65 | - |
Homo sapiens |