Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
cytosol | - |
Rattus norvegicus | 5829 | - |
microsome | - |
Homo sapiens | - |
- |
microsome | higher enzyme activity compared to cytosol | Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
bis(2-ethylhexyl)phthalate + H2O | Homo sapiens | - |
2-ethylhexyl phthalate + 2-ethylhexan-1-ol | - |
? | |
bis(2-ethylhexyl)phthalate + H2O | Rattus norvegicus | - |
2-ethylhexyl phthalate + 2-ethylhexan-1-ol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Homo sapiens | - |
intestine | - |
Rattus norvegicus | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
additional information | enzyme activity in human intestine is 2.4fold higher than that in human liver | Homo sapiens | - |
additional information | enzyme activity in rat intestine is 1.7fold less than that in rat liver | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
bis(2-ethylhexyl)phthalate + H2O | - |
Homo sapiens | 2-ethylhexyl phthalate + 2-ethylhexan-1-ol | - |
? | |
bis(2-ethylhexyl)phthalate + H2O | - |
Rattus norvegicus | 2-ethylhexyl phthalate + 2-ethylhexan-1-ol | - |
? |
General Information | Comment | Organism |
---|---|---|
evolution | an esterase-mediated pathway in rat liver might occur predominantly rather than in human liver although it is comparable between human and rat | Homo sapiens |
evolution | an esterase-mediated pathway in rat liver might occur predominantly rather than in human liver although it is comparable between human and rat | Rattus norvegicus |
metabolism | an esterase-mediated pathway in rat liver might occur predominantly rather than in human liver although it is comparable between human and rat | Homo sapiens |
metabolism | an esterase-mediated pathway in rat liver might occur predominantly rather than in human liver although it is comparable between human and rat | Rattus norvegicus |