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Literature summary for 3.1.1.59 extracted from

  • Hinton, A.C.; Hammock, B.D.
    In vitro expression and biochemical characterization of juvenile hormone esterase from Manduca sexta (2003), Insect Biochem. Mol. Biol., 33, 317-329.
    View publication on PubMed
Search for more literature for 3.1.1.59

Activating Compound

Activating Compound Comment Organism Structure
detergent activates at lower concentrations Manduca sexta
organic solvent activates at lower concentrations Manduca sexta

Application

Application Comment Organism
synthesis the high tolerance of organic solvents may make JHE useful in future applications as a synthetic catalyst Manduca sexta

Cloned(Commentary)

Cloned (Comment) Organism
full-length cDNA, expression in Hi5 cells from Trichoplusia ni Manduca sexta

Inhibitors

Inhibitors Comment Organism Structure
phosphoramidothiolate JHE is highly sensitive to certain phosphoramidothiolates Manduca sexta
trifluoroketone inhibitor JHE is highly sensitive Manduca sexta

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
juvenile hormone + H2O Manduca sexta plays an important role in the regulation of metamorphosis in caterpillars, JHE is implicated in additional roles in development and reproduction ?
-
 ?

Organic Solvent Stability

Organic Solvent Comment Organism
additional information high tolerance of organic solvents, organic solvents activate at lower concentrations, JHE remains significantly active even at high concentrations Manduca sexta

Organism

Organism UniProt Comment Textmining
Manduca sexta
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant JHE, partial Manduca sexta

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
juvenile hormone + H2O selective enzyme, hydrolyzes the methyl ester of juvenile hormone Manduca sexta ?
-
 ?
juvenile hormone + H2O plays an important role in the regulation of metamorphosis in caterpillars, JHE is implicated in additional roles in development and reproduction Manduca sexta ?
-
 ?

Synonyms

Synonyms Comment Organism
JHE
-
 Manduca sexta

pI Value

Organism Comment pI Value Maximum pI Value
Manduca sexta isoelectric focusing
-
 6