Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.56 extracted from

  • Hopkinson, D.A.; Mestriner, M.A.; Cortner, J.; Harris, H.
    Esterase D: a new human polymorphism (1973), Ann. Hum. Genet., 37, 119-137.
    View publication on PubMed
Search for more literature for 3.1.1.56

Inhibitors

Inhibitors Comment Organism Structure
additional information relatively insensitive to: 4-nitrophenyl phosphate and acetozolamide Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-methylumbelliferyl acetate + H2O Homo sapiens
-
 4-methylumbelliferone + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 3 isoenzymes: Es D1, Es D2-1, Es D2
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
erythrocyte
-
 Homo sapiens
-
gonad
-
 Homo sapiens
-
heart
-
 Homo sapiens
-
intestine
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
leukocyte
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
lung
-
 Homo sapiens
-
skeletal muscle
-
 Homo sapiens
-
spleen
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl acetate + H2O
-
 Homo sapiens 4-methylumbelliferone + acetate
-
 ?
4-methylumbelliferyl butyrate + H2O
-
 Homo sapiens 4-methylumbelliferone + butyrate
-
 ?
additional information acts on short chain acyl esters of 4-methylumbelliferone, but not on naphthyl, indoxyl or thiocholine esters Homo sapiens ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 5.5 methylumbelliferyl acetate, methylumbelliferyl butyrate Homo sapiens