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Literature summary for 3.1.1.47 extracted from

  • Corte-Real, R.; Gomes, R.N.; Castro-Faria-Neto, H.C.; Azambuja, P.; Garcia, E.S.
    The activity of platelet activating factor-acetyl hydrolase (PAF-AH) in the salivary glands of Rhodnius prolixus (2011), J. Insect Physiol., 57, 825-829.
    View publication on PubMed
Search for more literature for 3.1.1.47

Inhibitors

Inhibitors Comment Organism Structure
4-bromophenacyl bromide
-
 Rhodnius prolixus
additional information no inhibition by EGTA Rhodnius prolixus
N-tosyl-L-lysine chloromethyl ketone
-
 Rhodnius prolixus
N-tosyl-L-phenylalanyl chloromethyl ketone
-
 Rhodnius prolixus
pepstatin A
-
 Rhodnius prolixus
PMSF
-
 Rhodnius prolixus

Metals/Ions

Metals/Ions Comment Organism Structure
additional information PAF-AH activity is a Ca2+-independent enzyme Rhodnius prolixus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 gel filtration Rhodnius prolixus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
platelet activating factor + H2O Rhodnius prolixus
-
 acetate + deacetylated platelet activating factor
-
 ?

Organism

Organism UniProt Comment Textmining
Rhodnius prolixus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
saliva PAF-AH activity in the salivary gland homogenates is lower than in the saliva Rhodnius prolixus
-
salivary gland PAF-AH activity in the salivary gland homogenates is lower than in the saliva Rhodnius prolixus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-thio-[platelet activating factor] + H2O
-
 Rhodnius prolixus acetate + deacetylated 2-thio-[platelet activating factor]
-
 ?
platelet activating factor + H2O
-
 Rhodnius prolixus acetate + deacetylated platelet activating factor
-
 ?

Synonyms

Synonyms Comment Organism
PAF-AH
-
 Rhodnius prolixus
platelet activating factor-acetyl hydrolase
-
 Rhodnius prolixus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 salivary PAF-AH is stable at least for 4 h at 37°C Rhodnius prolixus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
 assay at Rhodnius prolixus