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Literature summary for 3.1.1.47 extracted from

  • Nakos, G.; Kitsiouli, E.; Hatzidaki, E.; Koulouras, V.; Touqui, L.; Lekka, M.E.
    Phospholipases A2 and platelet-activating-factor acetylhydrolase in patients with acute respiratory distress syndrome (2005), Crit. Care Med., 33, 772-779.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O Homo sapiens regulation of platelet-activating factor, enzyme could play an important role in the development or down regulation of inflammation in acute respiratory distress syndrome 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
?
oxidized phospholipids + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
patients with acute respiratory distress syndrome and control subjects, higher enzyme activity in the fluid and plasma of bronchoalveolar lavage from patients suffering from acute respiratory distress syndrome compared with the control group, lower enzyme activity in the cells of bronchoalveolar lavage from patients suffering from acute respiratory distress syndrome compared with the control group
-

Source Tissue

Source Tissue Comment Organism Textmining
bronchoalveolar lavage higher activity in fluid and plasma than in cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O regulation of platelet-activating factor, enzyme could play an important role in the development or down regulation of inflammation in acute respiratory distress syndrome Homo sapiens 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
?
oxidized phospholipids + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
platelet-activating-factor acetylhydrolase
-
Homo sapiens