BRENDA - Enzyme Database show
show all sequences of 3.1.1.43

Occurrence and some properties of a mercuri-activatable amino acid esterase from rat kidney microsomes

Kleine, R.; Meisel, P.; FEBS Lett. 37, 120-123 (1973)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Rattus norvegicus
-
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
HgCl2
activates
Rattus norvegicus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
kidney
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-leucine ethyl ester + H2O
-
80937
Rattus norvegicus
L-leucine + ethanol
-
80937
Rattus norvegicus
?
L-phenylalanine ethyl ester + H2O
-
80937
Rattus norvegicus
L-phenylalanine + ethanol
-
80937
Rattus norvegicus
?
L-tyrosine ethyl ester + H2O
-
80937
Rattus norvegicus
L-tyrosine + ethanol
-
80937
Rattus norvegicus
?
L-tyrosine propyl ester + H2O
-
80937
Rattus norvegicus
L-tyrosine + propanol
-
80937
Rattus norvegicus
?
p-hydroxyphenylpropionic acid ethyl ester + H2O
-
80937
Rattus norvegicus
p-hydroxyphenylpropionic acid + ethanol
-
80937
Rattus norvegicus
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
45
-
-
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Rattus norvegicus
-
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
HgCl2
activates
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
kidney
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-leucine ethyl ester + H2O
-
80937
Rattus norvegicus
L-leucine + ethanol
-
80937
Rattus norvegicus
?
L-phenylalanine ethyl ester + H2O
-
80937
Rattus norvegicus
L-phenylalanine + ethanol
-
80937
Rattus norvegicus
?
L-tyrosine ethyl ester + H2O
-
80937
Rattus norvegicus
L-tyrosine + ethanol
-
80937
Rattus norvegicus
?
L-tyrosine propyl ester + H2O
-
80937
Rattus norvegicus
L-tyrosine + propanol
-
80937
Rattus norvegicus
?
p-hydroxyphenylpropionic acid ethyl ester + H2O
-
80937
Rattus norvegicus
p-hydroxyphenylpropionic acid + ethanol
-
80937
Rattus norvegicus
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
45
-
-
Rattus norvegicus
Other publictions for EC 3.1.1.43
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
749442
Hossain
Purification and characteriza ...
Stenotrophomonas maltophilia
3 Biotech
8
173
2018
-
-
-
-
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6
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1
1
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1
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1
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8
1
1
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1
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1
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6
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1
1
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1
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8
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
730436
Sklyarenko
-
Recombinant alpha-amino ester ...
Acidovorax avenae, Acidovorax avenae VKPM B-9915
Moscow University Chem. Bull.
69
62-67
2014
1
-
1
-
1
-
-
-
-
-
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2
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2
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1
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1
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1
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1
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1
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2
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1
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1
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1
1
-
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-
728926
Zarubina
3D Structure modeling of alpha ...
Acidovorax avenae
Acta Naturae
5(4)
62-70
2013
-
1
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2
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6
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1
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6
-
-
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-
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-
-
1
1
-
-
-
729021
Kurochkina
-
alpha-Amino acid ester hydrola ...
Acetobacter pasteurianus, Acetobacter pasteurianus ATCC 6033, Acetobacter pasteurianus ATCC 9325, Acidovorax avenae, Acidovorax avenae CGMCC No. 2339, Acidovorax avenae VKM B-629, Acidovorax avenae VKPMB-9915, Flavobacterium sp., Flavobacterium sp. ATCC 9325, Gluconobacter oxydans, Gluconobacter oxydans ATCC 621, Homo sapiens, Mycoplana dimorpha, Mycoplana dimorpha IFO 13213, Protaminobacter alboflavus, Protaminobacter alboflavus IFO 13221, Pseudomonas danceae, Pseudomonas melanogenum, Pseudomonas melanogenum ATCC 17808, Pseudomonas melanogenum IFO 12020, Pseudomonas melanogenum KY3987, Pseudomonas melanogenum KY8540, Rattus norvegicus, Xanthomonas campestris, Xanthomonas campestris IFO 3835, Xanthomonas citri, Xanthomonas citri IFO 3835, Xanthomonas oryzae, Xanthomonas oryzae IFO 3995, Xanthomonas sp.
Appl. Biochem. Microbiol.
49
672-694
2013
-
8
4
-
3
-
-
35
-
-
9
3
-
30
-
-
1
-
-
4
-
-
92
10
15
-
-
23
18
-
-
-
-
8
-
-
8
4
-
-
3
-
-
-
-
35
-
-
9
3
-
-
-
1
-
4
-
-
92
10
15
-
-
23
18
-
-
8
-
21
21
-
18
18
729461
Ye
Changing the specificity of al ...
Acidovorax avenae
Biotechnol. Lett.
34
1719-1724
2012
-
-
1
-
4
-
-
4
-
-
-
1
-
1
-
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-
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-
-
-
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3
-
1
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4
1
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1
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4
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4
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1
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3
-
1
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4
1
-
-
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1
1
-
4
4
715846
Sun
Enhancing the intestinal absor ...
Homo sapiens
J. Med. Chem.
53
624-632
2010
-
-
-
-
-
-
-
4
-
-
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-
-
1
-
-
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3
-
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6
-
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4
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-
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-
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4
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3
-
-
6
-
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-
-
4
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-
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-
-
4
4
716273
Sun
Specificity of a prodrug-activ ...
Homo sapiens
Mol. Pharm.
7
2362-2368
2010
-
1
1
-
-
-
-
10
-
-
-
-
-
2
-
-
1
1
-
2
-
-
12
-
1
-
-
9
1
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
1
-
2
-
-
12
-
1
-
-
9
1
-
-
-
-
1
1
-
9
9
693224
Lai
Molecular basis of prodrug act ...
Homo sapiens
J. Biol. Chem.
283
9318-9327
2008
-
1
1
1
2
-
-
-
-
1
-
2
-
2
-
-
1
-
-
-
14
-
18
-
1
-
-
-
1
-
-
-
-
-
-
-
1
1
-
1
2
-
-
-
-
-
-
1
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2
-
-
-
1
-
-
14
-
18
-
1
-
-
-
1
-
-
-
-
-
-
-
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-
674752
Barends
Acetobacter turbidans alpha -A ...
Acetobacter pasteurianus
J. Biol. Chem.
281
5804-5810
2006
-
-
-
1
2
-
-
2
-
-
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-
2
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1
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1
1
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1
2
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2
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1
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1
1
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-
649217
Barends
Acetobacter turbidans alpha-am ...
Acetobacter pasteurianus
Acta Crystallogr. Sect. D
59
2237-2241
2003
-
-
1
1
-
-
-
-
-
-
-
1
-
2
-
-
1
-
-
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-
2
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1
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1
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1
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1
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2
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-
652406
Barends
The sequence and crystal struc ...
Xanthomonas citri
J. Biol. Chem.
278
23076-23084
2003
-
-
1
1
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-
-
-
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2
1
-
3
-
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1
-
-
-
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2
1
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1
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1
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2
1
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1
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2
1
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-
-
-
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-
-
-
-
-
-
-
-
649372
Polderman-Tijmes
Cloning, sequence analysis, an ...
Acetobacter pasteurianus
Appl. Environ. Microbiol.
68
211-218
2002
-
-
1
-
-
-
-
7
-
-
2
1
-
4
-
-
1
-
-
-
1
-
8
1
-
-
-
8
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
7
-
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2
1
-
-
-
1
-
-
1
-
8
1
-
-
-
8
-
-
-
-
-
-
-
-
-
-
652282
Polderman-Tijmes
Identification of the catalyti ...
Acetobacter pasteurianus
J. Biol. Chem.
277
28474-28482
2002
-
-
1
-
7
-
1
1
-
-
-
1
-
2
-
-
1
-
-
-
-
-
4
-
-
-
-
1
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1
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7
-
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1
-
1
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-
1
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-
-
1
-
-
-
-
4
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
651785
Sugihara
A novel alpha-amino-acid ester ...
Bacillus mycoides
J. Biochem.
130
119-126
2001
-
-
-
-
-
-
1
-
-
-
2
1
-
2
-
-
1
-
-
-
1
-
22
1
1
1
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
1
-
-
-
1
-
-
1
-
22
1
1
1
-
1
1
1
-
1
-
-
-
-
-
-
652946
Fernandez-Lafuente
-
Stabilization of a tetrameric ...
Acetobacter pasteurianus
J. Mol. Catal. B
11
633-638
2001
-
-
-
-
-
1
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
1
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
80938
MacNaugthan
Importance of enzyme and solve ...
Acetobacter pasteurianus
Enzyme Microb. Technol.
15
114-119
1993
-
-
-
-
-
-
-
-
-
-
-
-
22
1
-
-
-
-
-
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-
-
2
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-
-
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-
-
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-
22
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
80933
Kato
-
Purification of alpha-amino ac ...
Acetobacter pasteurianus, Gluconobacter oxydans, Komagataeibacter xylinus, Mycoplana dimorpha, Protaminobacter alboflavus, Pseudomonas melanogenum, Stenotrophomonas maltophilia, Xanthomonas citri, Xanthomonas oryzae
Agric. Biol. Chem.
44
1069-1074
1980
-
-
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4
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9
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1
1
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1
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2
2
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4
-
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1
1
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-
1
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
80934
Kato
-
Substrate specificity of alpha ...
Xanthomonas citri
Agric. Biol. Chem.
44
1075-1081
1980
-
-
-
-
-
-
3
3
-
-
-
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1
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-
-
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-
47
-
1
1
2
3
1
1
2
-
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-
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-
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3
-
3
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47
-
1
1
2
3
1
1
2
-
-
-
-
-
-
-
80935
Kato
-
Kinetics of acyl transfer by a ...
Xanthomonas citri
Agric. Biol. Chem.
44
1083-1088
1980
-
-
-
-
-
-
1
1
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-
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1
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1
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1
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1
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1
-
-
-
-
-
-
-
-
-
-
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-
-
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-
80936
Takahashi
Substrate specificity of an al ...
Acetobacter pasteurianus
Biochem. J.
137
497-503
1974
-
-
-
-
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-
3
9
-
-
-
-
-
2
-
-
1
-
-
-
1
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
9
-
-
-
-
-
-
-
1
-
-
1
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
80937
Kleine
Occurrence and some properties ...
Rattus norvegicus
FEBS Lett.
37
120-123
1973
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
-
1
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5
-
1
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1
1
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1
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5
-
1
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