BRENDA - Enzyme Database show
show all sequences of 3.1.1.43

Substrate specificity of alpha-amino acid hydrolase from Xanthomonas citri

Kato, K.; Kawahara, K.; Takahashi, T.; Kakinuma, A.; Agric. Biol. Chem. 44, 1075-1081 (1980)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
CuSO4
-
Xanthomonas citri
FeSO4
-
Xanthomonas citri
HgCl2
-
Xanthomonas citri
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.99
-
cephalexin
-
Xanthomonas citri
5.08
-
7-amino-3-deacetoxycephalosporanic acid
-
Xanthomonas citri
8.26
-
D-alpha-phenylglycine methyl ester
-
Xanthomonas citri
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Xanthomonas citri
-
IFO 3835
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-aminoisobutyric acid methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
alpha-aminoisobutyric acid methyl ester + H2O
-
80934
Xanthomonas citri
alpha-aminoisobutyric acid + methanol
-
80934
Xanthomonas citri
?
ampicillin + H2O
-
80934
Xanthomonas citri
(R)-2-phenylglycine + 6-aminopenicillanic acid
-
-
-
?
cephalexin + H2O
-
80934
Xanthomonas citri
7-amino-3-deacetoxycephalosporanic acid + phenylglycine
-
-
-
r
cephalexin + H2O
-
80934
Xanthomonas citri
D-phenylglycine + 7-aminodesacetoxycephalosporanic acid
-
-
-
?
cephaloglycin + H2O
-
80934
Xanthomonas citri
?
-
-
-
?
D-alanine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-alanine methyl ester + H2O
-
80934
Xanthomonas citri
D-alanine + methanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine ethyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
ethanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine ethyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + ethanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine isopropyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
isopropanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine isopropyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + isopropanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + 6-aminopenicillanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + 7-aminocephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + methanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-butyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
butanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-butyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + n-butanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-propyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
n-propanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-propyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + n-propanol
-
80934
Xanthomonas citri
?
D-leucine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-leucine methyl ester + H2O
-
80934
Xanthomonas citri
D-leucine + methanol
-
80934
Xanthomonas citri
?
D-methionine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-methionine methyl ester + H2O
-
80934
Xanthomonas citri
D-methionine + methanol
-
80934
Xanthomonas citri
?
D-serine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-serine methyl ester + H2O
-
80934
Xanthomonas citri
D-serine + methanol
-
80934
Xanthomonas citri
?
DL-alpha-aminobutyric acid methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
DL-alpha-aminobutyric acid methyl ester + H2O
-
80934
Xanthomonas citri
DL-alpha-aminobutyric acid + methanol
-
80934
Xanthomonas citri
?
DL-threonine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
DL-threonine methyl ester + H2O
-
80934
Xanthomonas citri
DL-threonine + methanol
-
80934
Xanthomonas citri
?
glycine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
glycine methyl ester + H2O
-
80934
Xanthomonas citri
glycine + methanol
-
80934
Xanthomonas citri
?
L-alpha-phenylglycine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + cephalexin
-
80934
Xanthomonas citri
?
L-arginine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-arginine methyl ester + H2O
-
80934
Xanthomonas citri
L-arginine + methanol
-
80934
Xanthomonas citri
?
L-cysteine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-cysteine methyl ester + H2O
-
80934
Xanthomonas citri
L-cysteine + methanol
-
80934
Xanthomonas citri
?
L-glutamic acid methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-glutamic acid methyl ester + H2O
-
80934
Xanthomonas citri
L-glutamic acid + methanol
-
80934
Xanthomonas citri
?
L-lysine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-lysine methyl ester + H2O
-
80934
Xanthomonas citri
L-lysine + methanol
-
80934
Xanthomonas citri
?
L-methionine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-methionine methyl ester + H2O
-
80934
Xanthomonas citri
L-methionine + methanol
-
80934
Xanthomonas citri
?
L-phenylalanine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-phenylalanine methyl ester + H2O
-
80934
Xanthomonas citri
L-phenylalanine + methanol
-
80934
Xanthomonas citri
?
L-serine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-serine methyl ester + H2O
-
80934
Xanthomonas citri
L-serine + methanol
-
80934
Xanthomonas citri
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
35
-
hydrolysis and acyl group transfer
Xanthomonas citri
Temperature Range [°C]
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
-
40
-
Xanthomonas citri
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
30
-
no loss of activity after 15 min, pH 6
Xanthomonas citri
50
-
completely inactivated within 15 min, pH 6
Xanthomonas citri
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
3200
-
cephalexin
cephalexin hydrolysis
Xanthomonas citri
6600
-
D-alpha-phenylglycine methyl ester
acyl transfer from D-alpha-phenylglycine methyl ester to 7-amino-3-deacetoxycephalosporanic acid
Xanthomonas citri
11100
-
D-alpha-phenylglycine methyl ester
hydrolysis of D-alpha-phenylglycine methyl ester
Xanthomonas citri
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.4
-
hydrolysis and acyl group transfer
Xanthomonas citri
pH Range
pH Minimum
pH Maximum
Commentary
Organism
6.4
-
-
Xanthomonas citri
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
4
9
stable, 16 h, 0°C
Xanthomonas citri
5.5
7.5
stable, 1 h, 30°C
Xanthomonas citri
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
CuSO4
-
Xanthomonas citri
FeSO4
-
Xanthomonas citri
HgCl2
-
Xanthomonas citri
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.99
-
cephalexin
-
Xanthomonas citri
5.08
-
7-amino-3-deacetoxycephalosporanic acid
-
Xanthomonas citri
8.26
-
D-alpha-phenylglycine methyl ester
-
Xanthomonas citri
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-aminoisobutyric acid methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
alpha-aminoisobutyric acid methyl ester + H2O
-
80934
Xanthomonas citri
alpha-aminoisobutyric acid + methanol
-
80934
Xanthomonas citri
?
ampicillin + H2O
-
80934
Xanthomonas citri
(R)-2-phenylglycine + 6-aminopenicillanic acid
-
-
-
?
cephalexin + H2O
-
80934
Xanthomonas citri
7-amino-3-deacetoxycephalosporanic acid + phenylglycine
-
-
-
r
cephalexin + H2O
-
80934
Xanthomonas citri
D-phenylglycine + 7-aminodesacetoxycephalosporanic acid
-
-
-
?
cephaloglycin + H2O
-
80934
Xanthomonas citri
?
-
-
-
?
D-alanine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-alanine methyl ester + H2O
-
80934
Xanthomonas citri
D-alanine + methanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine ethyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
ethanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine ethyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + ethanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine isopropyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
isopropanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine isopropyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + isopropanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + 6-aminopenicillanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + 7-aminocephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine methyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + methanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-butyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
butanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-butyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + n-butanol
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-propyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
n-propanol + cephalexin
-
80934
Xanthomonas citri
?
D-alpha-phenylglycine n-propyl ester + H2O
-
80934
Xanthomonas citri
D-alpha-phenylglycine + n-propanol
-
80934
Xanthomonas citri
?
D-leucine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-leucine methyl ester + H2O
-
80934
Xanthomonas citri
D-leucine + methanol
-
80934
Xanthomonas citri
?
D-methionine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-methionine methyl ester + H2O
-
80934
Xanthomonas citri
D-methionine + methanol
-
80934
Xanthomonas citri
?
D-serine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
D-serine methyl ester + H2O
-
80934
Xanthomonas citri
D-serine + methanol
-
80934
Xanthomonas citri
?
DL-alpha-aminobutyric acid methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
DL-alpha-aminobutyric acid methyl ester + H2O
-
80934
Xanthomonas citri
DL-alpha-aminobutyric acid + methanol
-
80934
Xanthomonas citri
?
DL-threonine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
DL-threonine methyl ester + H2O
-
80934
Xanthomonas citri
DL-threonine + methanol
-
80934
Xanthomonas citri
?
glycine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
glycine methyl ester + H2O
-
80934
Xanthomonas citri
glycine + methanol
-
80934
Xanthomonas citri
?
L-alpha-phenylglycine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + cephalexin
-
80934
Xanthomonas citri
?
L-arginine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-arginine methyl ester + H2O
-
80934
Xanthomonas citri
L-arginine + methanol
-
80934
Xanthomonas citri
?
L-cysteine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-cysteine methyl ester + H2O
-
80934
Xanthomonas citri
L-cysteine + methanol
-
80934
Xanthomonas citri
?
L-glutamic acid methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-glutamic acid methyl ester + H2O
-
80934
Xanthomonas citri
L-glutamic acid + methanol
-
80934
Xanthomonas citri
?
L-lysine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-lysine methyl ester + H2O
-
80934
Xanthomonas citri
L-lysine + methanol
-
80934
Xanthomonas citri
?
L-methionine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-methionine methyl ester + H2O
-
80934
Xanthomonas citri
L-methionine + methanol
-
80934
Xanthomonas citri
?
L-phenylalanine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-phenylalanine methyl ester + H2O
-
80934
Xanthomonas citri
L-phenylalanine + methanol
-
80934
Xanthomonas citri
?
L-serine methyl ester + 7-amino-3-deacetoxycephalosporanic acid
-
80934
Xanthomonas citri
methanol + ?
-
80934
Xanthomonas citri
?
L-serine methyl ester + H2O
-
80934
Xanthomonas citri
L-serine + methanol
-
80934
Xanthomonas citri
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
35
-
hydrolysis and acyl group transfer
Xanthomonas citri
Temperature Range [°C] (protein specific)
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
-
40
-
Xanthomonas citri
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
30
-
no loss of activity after 15 min, pH 6
Xanthomonas citri
50
-
completely inactivated within 15 min, pH 6
Xanthomonas citri
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
3200
-
cephalexin
cephalexin hydrolysis
Xanthomonas citri
6600
-
D-alpha-phenylglycine methyl ester
acyl transfer from D-alpha-phenylglycine methyl ester to 7-amino-3-deacetoxycephalosporanic acid
Xanthomonas citri
11100
-
D-alpha-phenylglycine methyl ester
hydrolysis of D-alpha-phenylglycine methyl ester
Xanthomonas citri
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.4
-
hydrolysis and acyl group transfer
Xanthomonas citri
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
6.4
-
-
Xanthomonas citri
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
4
9
stable, 16 h, 0°C
Xanthomonas citri
5.5
7.5
stable, 1 h, 30°C
Xanthomonas citri
Other publictions for EC 3.1.1.43
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
749442
Hossain
Purification and characteriza ...
Stenotrophomonas maltophilia
3 Biotech
8
173
2018
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6
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1
1
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1
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1
-
8
1
1
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1
-
1
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-
-
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6
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