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Literature summary for 3.1.1.4 extracted from
- Tailoring the pH dependence of human non-pancreatic secretory phospholipase A2 by engineering surface charges (2013), Appl. Biochem. Biotechnol., 171, 1454-1464.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E89K | surface charge replacements, mutant shows increased activitiy at neutral pH, 2.3 times that of the wild-type enzyme at pH 7 | Homo sapiens |
| R100E | surface charge replacements, mutant shows increased activitiy at neutral pH, 2.8, and times that of the wild-type enzyme at pH 7 | Homo sapiens |
| R42E | surface charge replacements, mutant shows increased activitiy at neutral pH, 2.3times that of the wild-type enzyme at pH 7 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2-dimyristoyl-sn-glycero-3-phosphocholine + H2O | - |
Homo sapiens | 1-myristoyl-sn-glycero-3-phosphocholine + myristic acid | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Non-pancreatic secretory phospholipase A2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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