Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methyl-arachidonyl fluorophosphonate | an irreversible inhibitor | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | GIVA phospholipase A2 associates with natural membranes in response to an increase in intracellular Ca2+ along with increases in certain lipid mediators, overview | Homo sapiens | 16020 | - |
additional information | the isolated C2 domain binds a phospholipid membrane in the presence of Ca2+ in vitro | Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P47712 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | inhibitor plus phospholipid vesicles cause a decreases at the C2 domain as well as charged residues on the putative membrane binding surface of the catalytic domain revealing the binding sites of the enzyme to the lipid surface, hypothetical model of initial membrane binding before lid opening, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cPLA2 | - |
Homo sapiens |
GIVA phospholipase A2 | - |
Homo sapiens |
group IVA cytosolic phospholipase A2 | - |
Homo sapiens |
group IVA phospholipase A2 | - |
Homo sapiens |