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Literature summary for 3.1.1.4 extracted from

  • Kamble, R.R.; Belgur, S.S.; Aladkatti, R.; Khazi, I.A.
    Synthesis and evaluation of benzophenone oximes derivatized with sydnone as inhibitors of secretory phospholipase A2 with anti-inflammatory activity (2009), Chem. Pharm. Bull., 57, 16-21.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
3-[4'-(hydroxyimino-p-tolyl-methyl)-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4'-(hydroxyimino-p-tolyl-methyl)-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Naja naja
3-[4'-(hydroxyimino-p-tolyl-methyl)-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4'-(hydroxyimino-p-tolyl-methyl)-phenyl]-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4'-(hydroxyimino-p-tolyl-methyl)-phenyl]-sydnone in vivo edema inducing activity, overview Naja naja
3-[4'-(hydroxyimino-p-tolyl-methyl)-phenyl]-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4'-(hydroxyimino-phenyl-methyl)-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4'-(hydroxyimino-phenyl-methyl)-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Naja naja
3-[4'-(hydroxyimino-phenyl-methyl)-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4'-(hydroxyimino-phenyl-methyl)-phenyl]-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4'-(hydroxyimino-phenyl-methyl)-phenyl]-sydnone in vivo edema inducing activity, overview Naja naja
3-[4'-(hydroxyimino-phenyl-methyl)-phenyl]-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4-[hydroxyimino-(4'-n-butyl-phenyl)-methyl]-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4-[hydroxyimino-(4'-n-butyl-phenyl)-methyl]-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Naja naja
3-[4-[hydroxyimino-(4'-n-butyl-phenyl)-methyl]-phenyl]-4-phenyl-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4-[hydroxyimino-(4'-n-butyl-phenyl)-methyl]-phenyl]-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4-[hydroxyimino-(4'-n-butyl-phenyl)-methyl]-phenyl]-sydnone in vivo edema inducing activity, overview Naja naja
3-[4-[hydroxyimino-(4'-n-butyl-phenyl)-methyl]-phenyl]-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4-[hydroxyimino-(4'-n-propyl-phenyl)-methyl]-phenyl]-4-phenylsydnone in vivo edema inducing activity, overview Daboia russelii
3-[4-[hydroxyimino-(4'-n-propyl-phenyl)-methyl]-phenyl]-4-phenylsydnone in vivo edema inducing activity, overview Naja naja
3-[4-[hydroxyimino-(4'-n-propyl-phenyl)-methyl]-phenyl]-4-phenylsydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
3-[4-[hydroxyimino-(4'-n-propyl-phenyl)-methyl]-phenyl]-sydnone in vivo edema inducing activity, overview Daboia russelii
3-[4-[hydroxyimino-(4'-n-propyl-phenyl)-methyl]-phenyl]-sydnone in vivo edema inducing activity, overview Naja naja
3-[4-[hydroxyimino-(4'-n-propyl-phenyl)-methyl]-phenyl]-sydnone in vivo edema inducing activity, overview Trimeresurus malabaricus
luffariellin B
-
 Daboia russelii
luffariellin B
-
 Naja naja
luffariellin B
-
 Trimeresurus malabaricus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretory PLA2 Daboia russelii
-
-
extracellular secretory PLA2 Naja naja
-
-
extracellular secretory PLA2 Trimeresurus malabaricus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activates Daboia russelii
Ca2+ activates Naja naja
Ca2+ activates Trimeresurus malabaricus

Organism

Organism UniProt Comment Textmining
Daboia russelii
-
-
-
Naja naja
-
-
-
Trimeresurus malabaricus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Daboia russelii
-
venom
-
 Naja naja
-
venom
-
 Trimeresurus malabaricus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information determination of the cytolytic activity od sPLA2 using oleate-labelled, autoclaved Escherichia coli cells as substrate, overview Daboia russelii ?
-
 ?
additional information determination of the cytolytic activity od sPLA2 using oleate-labelled, autoclaved Escherichia coli cells as substrate, overview Naja naja ?
-
 ?
additional information determination of the cytolytic activity od sPLA2 using oleate-labelled, autoclaved Escherichia coli cells as substrate, overview Trimeresurus malabaricus ?
-
 ?

Synonyms

Synonyms Comment Organism
secretory phospholipase A2
-
 Daboia russelii
secretory phospholipase A2
-
 Naja naja
secretory phospholipase A2
-
 Trimeresurus malabaricus
sPLA2
-
 Daboia russelii
sPLA2
-
 Naja naja
sPLA2
-
 Trimeresurus malabaricus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Daboia russelii
37
-
 assay at Naja naja
37
-
 assay at Trimeresurus malabaricus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 indirect hemolytic assay at Daboia russelii
7.5
-
 indirect hemolytic assay at Naja naja
7.5
-
 indirect hemolytic assay at Trimeresurus malabaricus
8
-
 enzymatic assay at Daboia russelii
8
-
 enzymatic assay at Naja naja
8
-
 enzymatic assay at Trimeresurus malabaricus