Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Calloselasma rhodostoma | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
13871 | - |
x * 13871, mass spectrometry, x * 14000, SDS-PAGE | Calloselasma rhodostoma |
14000 | - |
x * 13871, mass spectrometry, x * 14000, SDS-PAGE | Calloselasma rhodostoma |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Calloselasma rhodostoma | Cr-IV 1 shows a rapid cytolytic effect on mouse skeletal muscle myoblasts and myotubes in culture. Cr-IV 1 induces myonecrosis and edema upon intramuscular and intravenous injections, respectively, in mice | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Calloselasma rhodostoma | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from venom by gel filtration and C18 reverse phase HPLC | Calloselasma rhodostoma |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Calloselasma rhodostoma | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitro-3-(octanoyloxy)benzoic acid + H2O | a synthetic chromogenic substrate | Calloselasma rhodostoma | ? | - |
? | |
additional information | Cr-IV 1 shows a rapid cytolytic effect on mouse skeletal muscle myoblasts and myotubes in culture. Cr-IV 1 induces myonecrosis and edema upon intramuscular and intravenous injections, respectively, in mice | Calloselasma rhodostoma | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 13871, mass spectrometry, x * 14000, SDS-PAGE | Calloselasma rhodostoma |
More | determination of the amino acid composition, overview | Calloselasma rhodostoma |
Synonyms | Comment | Organism |
---|---|---|
Cr-IV 1 | - |
Calloselasma rhodostoma |
More | Cr-IV 1 as a member of the D49 PLA2 family | Calloselasma rhodostoma |
Myotoxin | - |
Calloselasma rhodostoma |
phospholipase A2 D49 | - |
Calloselasma rhodostoma |
PLA2 | - |
Calloselasma rhodostoma |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Calloselasma rhodostoma |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Calloselasma rhodostoma |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Calloselasma rhodostoma | sequence calculation | - |
8 |