Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DNA containing thymine glycol | i.e. MAFP, a specific PLA2 inhibitor | Pseudomonas aeruginosa | |
prostaglandin PGE2 | - |
Pseudomonas aeruginosa | |
prostaglandin PGI2 | - |
Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Pseudomonas aeruginosa | infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview | ? | - |
? | |
additional information | Pseudomonas aeruginosa PA103 | infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Pseudomonas aeruginosa PA103 | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview | Pseudomonas aeruginosa PA103 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cytotoxin ExoU | - |
Pseudomonas aeruginosa |