Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.4 extracted from

  • Sundell, I.B.; Aziz, K.A.; Zuzel, M.; Theakston, R.D.G.
    The role of phospholipases A2 in the stimulation of neutrophil motility by cobra venoms (2003), Toxicon, 41, 459-468.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
aristolochic acid partial inhibition Naja mossambica
aristolochic acid partial inhibition Naja naja
methyl arachidonyl fluorophosphonate almost complete inhibition Naja mossambica
methyl arachidonyl fluorophosphonate almost complete inhibition Naja naja

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Naja mossambica stimulates CD11b translocation from the PMN granule store to the plasma membrane and enhances neutrophil motility on collagen-coated surfaces, first causes a non-enzymatic stimulation of PMN leading to the activation of cytosolic PMN PLA2 production and of arachidonate metabolites involved in stimulation of PMN degranulation and motility ?
-
 ?
additional information Naja naja stimulates CD11b translocation from the polymorph nuclear granule store to the plasma membrane and enhances neutrophil motility on collagen-coated surfaces, first causes a non-enzymatic stimulation of PMN leading to the activation of cytosolic PMN PLA2 production and of arachidonate metabolites involved in stimulation of PMN degranulation and motility ?
-
 ?

Organism

Organism UniProt Comment Textmining
Naja mossambica
-
-
-
Naja naja
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Naja naja
-
venom
-
 Naja mossambica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information stimulates CD11b translocation from the PMN granule store to the plasma membrane and enhances neutrophil motility on collagen-coated surfaces, first causes a non-enzymatic stimulation of PMN leading to the activation of cytosolic PMN PLA2 production and of arachidonate metabolites involved in stimulation of PMN degranulation and motility Naja mossambica ?
-
 ?
additional information stimulates CD11b translocation from the polymorph nuclear granule store to the plasma membrane and enhances neutrophil motility on collagen-coated surfaces, first causes a non-enzymatic stimulation of PMN leading to the activation of cytosolic PMN PLA2 production and of arachidonate metabolites involved in stimulation of PMN degranulation and motility Naja naja ?
-
 ?