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Literature summary for 3.1.1.4 extracted from

  • Lee, D.; Won, J.H.; Auh, C.K.; Park, Y.M.
    Purification and characterization of a cytosolic phospholipase A2 from rat liver (2003), Mol. Cells, 16, 361-367.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
arachidonyl trifluoromethyl ketone
-
 Rattus norvegicus
KCl strong inhibition Rattus norvegicus
NaCl strong inhibition Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.83
-
 L-1-acyl-2-arachidonyl-sn-glycerol-3-phosphatidylethanolamine pH 7.5 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
197000
-
 gel filtration Rattus norvegicus
200000
-
 SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-1-acyl-2-arachidonyl-sn-glycerol-3-phosphatidylethanolamine + H2O
-
 Rattus norvegicus ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 200000, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
7 8.5 no activity below pH 7 or above pH 8.5 Rattus norvegicus