Any feedback?
Literature summary for 3.1.1.4 extracted from
- Purification of a basic phospholipase A2 from Indian Saw-Scawled Viper (Echis carinatus) venom: characterization of antigenic, catalytic and pharmacological properties (1994), Toxicon, 32, 1187-1196.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| anti-peptide antibody | - |
Echis carinatus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.25 | - |
phosphatidylcholine | - |
Echis carinatus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Echis carinatus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 13500 | - |
gel filtration | Echis carinatus |
| 14000 | - |
SDS-PAGE | Echis carinatus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospholipids + H2O | Echis carinatus | presynaptic neurotoxicity of neutral PLA2 | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Echis carinatus | - |
Indian Saw-Scawled Viper | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| column chromatography, electrophoresis, EC-IV-PLA2, 2.3fold | Echis carinatus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Echis carinatus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.4 | - |
substrate: phosphatidylcholine | Echis carinatus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylcholine + H2O | - |
Echis carinatus | 1-acylglycerophosphocholine + fatty acid | - |
? | |
| phospholipids + H2O | presynaptic neurotoxicity of neutral PLA2 | Echis carinatus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | 55 | EC-IV-PLA2 | Echis carinatus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8 | EC-IV-PLA2 | Echis carinatus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
