BRENDA - Enzyme Database
show all sequences of 3.1.1.32

Purification, characterization, molecular cloning and extracellular production of a phospholipase A1 from Streptomyces albidoflavus NA297

Sugimori, D.; Kano, K.; Matsumoto, Y.; FEBS open bio 2, 318-327 (2012)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene pla, DNA and amino acid sequence determination and analysis, expression and extracellular production of the recombinant enzyme in Streptomyces lividans from expression vector pUC702/pla
Streptomyces albidoflavus
Engineering
Amino acid exchange
Commentary
Organism
H218A
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
H218R
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S11A
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11D
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11E
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11T
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11Y
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S216A
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S216D
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S216E
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S216T
site-directed mutagenesis, the mutant shows 80-90% reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S216Y
site-directed mutagenesis, the mutant shows 80-90% reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
Inhibitors
Inhibitors
Commentary
Organism
Structure
2-mercaptoethanol
weak inhibition
Streptomyces albidoflavus
Ca2+
up to 0.1 mM
Streptomyces albidoflavus
Fe2+
-
Streptomyces albidoflavus
Fe3+
-
Streptomyces albidoflavus
additional information
the enzyme is not inhibited by EDTA and DTT
Streptomyces albidoflavus
PMSF
weak inhibition
Streptomyces albidoflavus
SDS
-
Streptomyces albidoflavus
Triton X-100
weak inhibition at up to 0.23% w/v
Streptomyces albidoflavus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.38
-
phosphatidic acid
pH 7.2, 50C, recombinant enzyme
Streptomyces albidoflavus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
additional information
the enzyme possesses a 33-residue N-terminal signal secretion sequence
Streptomyces albidoflavus
-
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Ca2+
activates at 10 mM
Streptomyces albidoflavus
additional information
metal ion-independent phospholipase A1
Streptomyces albidoflavus
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
27199
-
1 * 27199, mature protein, seuence calculation, 1 * 28000, recombinant extracellular enzyme, SDS-PAGE
Streptomyces albidoflavus
28000
-
DLS analysis
Streptomyces albidoflavus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Streptomyces albidoflavus
K0J3J2
isolated from Japanese soil, gene pla
-
Streptomyces albidoflavus NA297
K0J3J2
isolated from Japanese soil, gene pla
-
Purification (Commentary)
Commentary
Organism
recombinant extracellular enzyme to homogeneity from the culture supernatant by ammonium sulfate precipitation, hydrophobic interaction chromatography, and anion exchange chromatography
Streptomyces albidoflavus
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
588
2873
pH 7.2, 50C, purified recombinant enzyme
Streptomyces albidoflavus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1,2-dimyristoyl-sn-glycero-3-phosphate + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
1,2-dimyristoyl-sn-glycero-3-phosphate + H2O
-
729743
Streptomyces albidoflavus NA297
?
-
-
-
?
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine + H2O
-
729743
Streptomyces albidoflavus NA297
?
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
729743
Streptomyces albidoflavus NA297
?
-
-
-
?
L-alpha-phosphatidyl-L-serine + H2O
substrate from Glycine max
729743
Streptomyces albidoflavus
2-acyl-1-glycerophosphoserine + a carboxylate
-
-
-
?
L-alpha-phosphatidylcholine + H2O
PLA1 activity for egg yolk lecithin hydrolysis, substrate from egg yolk or Glycine max
729743
Streptomyces albidoflavus
2-acylglycerophosphocholine + a carboxylate
-
-
-
?
L-alpha-phosphatidylglycerol + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
L-alpha-phosphatidylinositol + H2O
-
729743
Streptomyces albidoflavus
2-acyl-sn-glycero-3-phosphoinositol + a carboxylate
-
-
-
?
lecithin + H2O
from Glycine max
729743
Streptomyces albidoflavus
?
-
-
-
?
additional information
the substrate specificity is pH-dependent, the enzyme preferably hydrolyzes phosphatidic acid and phosphatidylserine at pH 7.2, it is active with lysophosphatidylcholine, but not with triglyceride and the 4-nitrophenyl ester of fatty acids, substrate specificity, overview. At the reaction equilibrium, the molar ratio of released free fatty acids (sn-1:sn-2) is 63:37
729743
Streptomyces albidoflavus
?
-
-
-
-
additional information
the substrate specificity is pH-dependent, the enzyme preferably hydrolyzes phosphatidic acid and phosphatidylserine at pH 7.2, it is active with lysophosphatidylcholine, but not with triglyceride and the 4-nitrophenyl ester of fatty acids, substrate specificity, overview. At the reaction equilibrium, the molar ratio of released free fatty acids (sn-1:sn-2) is 63:37
729743
Streptomyces albidoflavus NA297
?
-
-
-
-
phosphatidic acid + H2O
-
729743
Streptomyces albidoflavus
2-acyl-lysophosphatidic acid + a carboxylate
-
-
-
?
phosphatidic acid + H2O
-
729743
Streptomyces albidoflavus NA297
2-acyl-lysophosphatidic acid + a carboxylate
-
-
-
?
Subunits
Subunits
Commentary
Organism
monomer
1 * 27199, mature protein, seuence calculation, 1 * 28000, recombinant extracellular enzyme, SDS-PAGE
Streptomyces albidoflavus
Temperature Optimum [C]
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
50
-
-
Streptomyces albidoflavus
Temperature Range [C]
Temperature Minimum [C]
Temperature Maximum [C]
Commentary
Organism
20
70
activity range, profile overview
Streptomyces albidoflavus
Temperature Stability [C]
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
40
-
native and recombinant enzymes, stable at
Streptomyces albidoflavus
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
630
-
phosphatidic acid
pH 7.2, 50C, recombinant enzyme
Streptomyces albidoflavus
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.2
-
-
Streptomyces albidoflavus
pH Range
pH Minimum
pH Maximum
Commentary
Organism
4
11
activity range, profile overview
Streptomyces albidoflavus
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
5.6
9
recombinant enzyme, stable at
Streptomyces albidoflavus
7.2
9
native enzyme, stable at
Streptomyces albidoflavus
Cloned(Commentary) (protein specific)
Commentary
Organism
gene pla, DNA and amino acid sequence determination and analysis, expression and extracellular production of the recombinant enzyme in Streptomyces lividans from expression vector pUC702/pla
Streptomyces albidoflavus
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
H218A
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
H218R
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S11A
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11D
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11E
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11T
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S11Y
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S216A
site-directed mutagenesis, inactive mutant
Streptomyces albidoflavus
S216D
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S216E
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S216T
site-directed mutagenesis, the mutant shows 80-90% reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
S216Y
site-directed mutagenesis, the mutant shows 80-90% reduced activity compared to the wild-type enzyme
Streptomyces albidoflavus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2-mercaptoethanol
weak inhibition
Streptomyces albidoflavus
Ca2+
up to 0.1 mM
Streptomyces albidoflavus
Fe2+
-
Streptomyces albidoflavus
Fe3+
-
Streptomyces albidoflavus
additional information
the enzyme is not inhibited by EDTA and DTT
Streptomyces albidoflavus
PMSF
weak inhibition
Streptomyces albidoflavus
SDS
-
Streptomyces albidoflavus
Triton X-100
weak inhibition at up to 0.23% w/v
Streptomyces albidoflavus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.38
-
phosphatidic acid
pH 7.2, 50C, recombinant enzyme
Streptomyces albidoflavus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
additional information
the enzyme possesses a 33-residue N-terminal signal secretion sequence
Streptomyces albidoflavus
-
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Ca2+
activates at 10 mM
Streptomyces albidoflavus
additional information
metal ion-independent phospholipase A1
Streptomyces albidoflavus
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
27199
-
1 * 27199, mature protein, seuence calculation, 1 * 28000, recombinant extracellular enzyme, SDS-PAGE
Streptomyces albidoflavus
28000
-
DLS analysis
Streptomyces albidoflavus
Purification (Commentary) (protein specific)
Commentary
Organism
recombinant extracellular enzyme to homogeneity from the culture supernatant by ammonium sulfate precipitation, hydrophobic interaction chromatography, and anion exchange chromatography
Streptomyces albidoflavus
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
588
2873
pH 7.2, 50C, purified recombinant enzyme
Streptomyces albidoflavus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1,2-dimyristoyl-sn-glycero-3-phosphate + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
1,2-dimyristoyl-sn-glycero-3-phosphate + H2O
-
729743
Streptomyces albidoflavus NA297
?
-
-
-
?
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine + H2O
-
729743
Streptomyces albidoflavus NA297
?
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
729743
Streptomyces albidoflavus NA297
?
-
-
-
?
L-alpha-phosphatidyl-L-serine + H2O
substrate from Glycine max
729743
Streptomyces albidoflavus
2-acyl-1-glycerophosphoserine + a carboxylate
-
-
-
?
L-alpha-phosphatidylcholine + H2O
PLA1 activity for egg yolk lecithin hydrolysis, substrate from egg yolk or Glycine max
729743
Streptomyces albidoflavus
2-acylglycerophosphocholine + a carboxylate
-
-
-
?
L-alpha-phosphatidylglycerol + H2O
-
729743
Streptomyces albidoflavus
?
-
-
-
?
L-alpha-phosphatidylinositol + H2O
-
729743
Streptomyces albidoflavus
2-acyl-sn-glycero-3-phosphoinositol + a carboxylate
-
-
-
?
lecithin + H2O
from Glycine max
729743
Streptomyces albidoflavus
?
-
-
-
?
additional information
the substrate specificity is pH-dependent, the enzyme preferably hydrolyzes phosphatidic acid and phosphatidylserine at pH 7.2, it is active with lysophosphatidylcholine, but not with triglyceride and the 4-nitrophenyl ester of fatty acids, substrate specificity, overview. At the reaction equilibrium, the molar ratio of released free fatty acids (sn-1:sn-2) is 63:37
729743
Streptomyces albidoflavus
?
-
-
-
-
additional information
the substrate specificity is pH-dependent, the enzyme preferably hydrolyzes phosphatidic acid and phosphatidylserine at pH 7.2, it is active with lysophosphatidylcholine, but not with triglyceride and the 4-nitrophenyl ester of fatty acids, substrate specificity, overview. At the reaction equilibrium, the molar ratio of released free fatty acids (sn-1:sn-2) is 63:37
729743
Streptomyces albidoflavus NA297
?
-
-
-
-
phosphatidic acid + H2O
-
729743
Streptomyces albidoflavus
2-acyl-lysophosphatidic acid + a carboxylate
-
-
-
?
phosphatidic acid + H2O
-
729743
Streptomyces albidoflavus NA297
2-acyl-lysophosphatidic acid + a carboxylate
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
monomer
1 * 27199, mature protein, seuence calculation, 1 * 28000, recombinant extracellular enzyme, SDS-PAGE
Streptomyces albidoflavus
Temperature Optimum [C] (protein specific)
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
50
-
-
Streptomyces albidoflavus
Temperature Range [C] (protein specific)
Temperature Minimum [C]
Temperature Maximum [C]
Commentary
Organism
20
70
activity range, profile overview
Streptomyces albidoflavus
Temperature Stability [C] (protein specific)
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
40
-
native and recombinant enzymes, stable at
Streptomyces albidoflavus
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
630
-
phosphatidic acid
pH 7.2, 50C, recombinant enzyme
Streptomyces albidoflavus
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.2
-
-
Streptomyces albidoflavus
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
4
11
activity range, profile overview
Streptomyces albidoflavus
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
5.6
9
recombinant enzyme, stable at
Streptomyces albidoflavus
7.2
9
native enzyme, stable at
Streptomyces albidoflavus
General Information
General Information
Commentary
Organism
additional information
residue Ser11 is essential for the catalytic function of the enzyme, the active site may include residues Ser216 and His218
Streptomyces albidoflavus
General Information (protein specific)
General Information
Commentary
Organism
additional information
residue Ser11 is essential for the catalytic function of the enzyme, the active site may include residues Ser216 and His218
Streptomyces albidoflavus
KCat/KM [mM/s]
kcat/KM Value [1/mMs-1]
kcat/KM Value Maximum [1/mMs-1]
Substrate
Commentary
Organism
Structure
265
-
phosphatidic acid
pH 7.2, 50C, recombinant enzyme
Streptomyces albidoflavus
KCat/KM [mM/s] (protein specific)
KCat/KM Value [1/mMs-1]
KCat/KM Value Maximum [1/mMs-1]
Substrate
Commentary
Organism
Structure
265
-
phosphatidic acid
pH 7.2, 50C, recombinant enzyme
Streptomyces albidoflavus
Other publictions for EC 3.1.1.32
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
749777
Beig-Mohammadi
-
Purification and characteriza ...
Trichoderma atroviride, Trichoderma atroviride ZB-ZH292
Biocatal. Agricult. Biotechnol.
13
176-181
2018
-
-
-
-
-
-
7
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
2
1
1
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
1
1
-
-
-
1
-
1
-
-
-
-
-
-
-
749788
Goni
-
Solvent-free enzymatic hydrol ...
Thermomyces lanuginosus
Biocatal. Biotransform.
36
341-351
2018
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
750103
Morisada
Suppression of respiratory gr ...
Saccharomyces cerevisiae
Biosci. Biotechnol. Biochem.
82
1633-1639
2018
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
752300
Rungsa
Purification and biochemical ...
Vespa tropica
Toxicon
148
74-84
2018
-
-
-
1
-
-
-
-
-
-
-
-
-
5
-
1
-
-
-
2
-
-
2
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
3
-
-
2
2
-
-
-
-
-
-
-
1
-
-
-
-
-
-
750476
Dard
Mutations in DDHD1, encoding ...
Homo sapiens
Eur. J. Med. Genet.
60
639-642
2017
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
751202
Xin
A comparative study on kineti ...
Thermomyces lanuginosus
J. Colloid Interface Sci.
488
149-154
2017
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
1
4
-
5
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
4
-
5
-
-
-
-
2
-
-
-
-
-
1
1
-
2
2
751408
Kaur
-
Optimization of phospholipase ...
Bacillus subtilis subsp. inaquosorum
J. Pure Appl. Microbiol.
11
829-836
2017
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
749810
Urafuji
Yor022c protein is a phosphol ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Biochem. Biophys. Res. Commun.
480
302-308
2016
-
-
1
-
1
-
-
-
4
1
-
-
-
60
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
750141
Lim
Cell-free synthesis of functi ...
Serratia sp. MK1
Biotechnol. Biofuels
9
159
2016
-
2
1
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
750579
Bang
Phospholipase A1-catalyzed hy ...
Thermomyces lanuginosus
Food Chem.
190
201-206
2016
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
751273
El Alaoui
A continuous spectrophotometr ...
Aspergillus oryzae
J. Lipid Res.
57
1589-1597
2016
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
751341
Li
-
Enhancing the performance of ...
Thermomyces lanuginosus
J. Mol. Catal. B
123
122-131
2016
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
749586
Iida
Phosphatidylserine-specific p ...
Homo sapiens
Anticancer Res.
35
1459-1464
2015
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
749593
Kerrinnes
Phospholipase A1 modulates th ...
Brucella melitensis bv. 1, Brucella melitensis bv. 1 ATCC 23456
Antimicrob. Agents Chemother.
59
6717-6724
2015
-
-
1
-
-
-
-
-
2
-
-
-
-
7
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
749838
Hama
-
Improved production of phosph ...
Aspergillus oryzae, Aspergillus oryzae NiaD300
Biochem. Eng. J.
96
1-6
2015
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
750165
Lim
Modeling and optimization of ...
Thermomyces lanuginosus
Biotechnol. Prog.
31
35-41
2015
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
729305
Aloulou
Kinetic and structural charact ...
Sus scrofa
Biochim. Biophys. Acta
1841
581-587
2014
-
-
-
-
1
-
-
-
-
1
-
1
-
3
-
-
-
-
-
1
1
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
1
-
3
-
1
-
-
-
1
-
-
-
-
2
2
-
-
-
729772
Zhao
Immobilized phospholipase A1-c ...
Fusarium oxysporum, Thermomyces lanuginosus
Food Chem.
157
132-140
2014
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
730037
Baba
Phosphatidic acid (PA)-preferr ...
Homo sapiens, Mus musculus
J. Biol. Chem.
289
11497-11511
2014
-
-
1
-
3
-
-
-
4
-
-
2
-
3
-
-
-
-
-
7
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
4
-
-
2
-
-
-
-
-
7
-
-
4
-
-
-
-
-
-
-
-
-
-
4
4
-
-
-
730100
Kunduri
Phosphatidic acid phospholipas ...
Drosophila melanogaster
J. Cell Biol.
206
79-96
2014
-
-
1
-
1
-
-
-
1
-
-
-
-
3
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
3
-
-
-
-
-
3
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
2
6
-
-
-
730833
Gaspar
VipD is a Rab5-activated phosp ...
Legionella pneumophila
Proc. Natl. Acad. Sci. USA
111
4560-4565
2014
2
-
1
-
6
-
1
-
1
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
6
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
730288
Murayama
Crystal structure of phospholi ...
Streptomyces albidoflavus, Streptomyces albidoflavus NA297
J. Struct. Biol.
182
192-196
2013
-
-
1
1
-
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
730354
Belaunzaran
Phospholipase A1: a novel viru ...
Trypanosoma cruzi
Mol. Biochem. Parasitol.
187
77-86
2013
-
-
1
-
-
-
-
-
2
-
1
-
-
3
-
-
1
-
-
3
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
1
-
3
-
-
1
1
1
-
-
-
1
-
-
-
1
1
1
1
-
-
731003
Sukprasert
Purification and structural ch ...
Vespa affinis
Toxicon
61
151-164
2013
-
-
1
-
-
-
-
-
1
-
-
-
-
6
-
1
-
-
-
2
-
-
-
1
-
-
1
-
-
-
-
-
-
4
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
1
-
-
1
-
-
-
-
4
-
1
1
-
-
-
716184
Hesse
Sequence and expression of the ...
Gallus gallus
Mol. Biol. Rep.
39
761-769
2012
-
-
1
-
-
-
-
-
1
-
-
-
-
5
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
729743
Sugimori
Purification, characterization ...
Streptomyces albidoflavus, Streptomyces albidoflavus NA297
FEBS open bio
2
318-327
2012
-
-
1
-
12
-
8
1
1
2
2
-
-
7
-
-
1
-
-
-
1
-
15
1
1
1
1
1
1
1
2
-
-
-
-
-
-
1
-
-
12
-
-
8
-
1
1
2
2
-
-
-
-
1
-
-
1
-
15
1
1
1
1
1
1
1
2
-
-
1
1
-
1
1
715386
Housley
The Rickettsia prowazekii ExoU ...
Rickettsia prowazekii
J. Bacteriol.
193
4634-4642
2011
1
-
1
-
2
-
1
-
-
-
-
1
-
4
-
-
1
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
2
-
-
1
-
-
-
-
-
1
-
-
-
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
715840
Bolen
The phospholipase A1 activity ...
Homo sapiens
J. Lipid Res.
52
958-970
2011
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
1
-
-
1
-
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
3
-
1
-
-
-
1
-
-
-
-
1
1
-
-
-
716710
Borodina
Expression of enzymatically in ...
Vespula vulgaris
PLoS ONE
6
e21267
2011
-
1
1
-
3
-
-
-
1
-
1
-
-
5
-
-
1
-
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
3
-
-
-
-
-
1
-
1
-
-
-
-
1
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
708202
Seismann
Recombinant phospholipase A1 ( ...
Vespula vulgaris
Clin. Mol. Allergy
8
7-7
2010
-
1
1
-
1
-
-
-
-
-
1
-
-
3
-
-
1
-
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
716165
Imae
Intracellular phospholipase A1 ...
Caenorhabditis elegans
Mol. Biol. Cell
21
3114-3124
2010
-
-
1
-
1
-
-
-
2
-
-
-
-
2
-
-
1
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
1
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
690664
Qiu
Endothelial lipase promotes ap ...
Homo sapiens
Arterioscler. Thromb. Vasc. Biol.
29
84-91
2009
-
-
1
-
1
-
1
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
707787
Mawatari
Simultaneous preparation of pu ...
Aspergillus oryzae
Biosci. Biotechnol. Biochem.
73
2621-2625
2009
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
709054
Morikawa
Intracellular phospholipase A1 ...
Homo sapiens
J. Biol. Chem.
284
26620-26630
2009
-
-
1
-
-
-
-
-
2
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
2
2
1
-
-
709425
Uyama
The tumor suppressor gene H-Re ...
Homo sapiens, Mus musculus, Rattus norvegicus
J. Lipid Res.
50
685-693
2009
4
-
3
-
1
-
3
-
3
3
1
-
-
6
-
-
3
-
-
2
-
-
10
1
-
-
-
-
-
-
-
-
-
-
-
4
-
3
-
-
1
-
-
3
-
-
3
3
1
-
-
-
-
3
-
2
-
-
10
1
-
-
-
-
-
-
-
-
-
3
3
-
-
-
690253
Chou
Crystallization and preliminar ...
Vespa basalis
Acta Crystallogr. Sect. F
64
1118-1120
2008
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690674
Shiu
Type 2 diabetes mellitus and e ...
Homo sapiens
Atherosclerosis
198
441-447
2008
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691003
Eydoux
Structure of human pancreatic ...
Homo sapiens
Biochemistry
47
9553-9564
2008
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691842
Badellino
Endothelial lipase is increase ...
Homo sapiens
Circulation
117
678-685
2008
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692119
Fu
A novel cold-adapted phospholi ...
Serratia sp. xJF1
Enzyme Microb. Technol.
42
187-194
2008
-
-
1
-
-
-
10
-
-
1
2
-
-
1
-
-
1
-
-
-
1
-
1
-
1
-
1
-
1
-
1
-
-
-
-
-
-
1
-
-
-
-
-
10
-
-
-
1
2
-
-
-
-
1
-
-
1
-
1
-
1
-
1
-
1
-
1
-
-
-
-
-
-
-
692411
Hiratsuka
-
Phospholipase A1 activity of c ...
Katsuwonus pelamis
Fish. Sci.
74
146-152
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
2
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
693275
Keller
A high-throughput screen for e ...
Homo sapiens
J. Biomol. Screen.
13
468-475
2008
-
-
1
-
-
-
2
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
693965
Nishihara
New phospholipase A1-producing ...
Pseudomonas sp.
Mar. Biotechnol.
10
382-387
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694548
Foell
Membrane-associated phospholip ...
Homo sapiens
Pediatr. Blood Cancer
51
228-234
2008
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694672
Seo
Heterologous expression, and b ...
Capsicum annuum
Plant J.
53
895-908
2008
-
-
1
-
-
-
-
-
-
-
1
1
-
5
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
678064
Richmond
The role and characterization ...
Trypanosoma brucei, Trypanosoma brucei 427
Biochem. J.
405
319-329
2007
1
-
-
-
1
-
15
1
-
1
2
2
-
3
-
-
-
-
-
1
1
-
4
-
1
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
15
-
1
-
1
2
2
-
-
-
-
-
1
1
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
678433
Chen
Phospholipid and fatty acid sp ...
Homo sapiens
Biochim. Biophys. Acta
1771
1319-1328
2007
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
2
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
678494
Aoki
Structure and function of extr ...
Bombyx mori, Cavia porcellus, Dolichovespula maculata, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus
Biochimie
89
197-204
2007
-
-
5
-
1
-
-
-
11
-
-
9
-
9
-
-
-
7
-
30
-
-
21
5
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
11
-
-
9
-
-
-
-
-
30
-
-
21
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
679553
Kim
-
Phospholipase A1-catalyzed syn ...
Fusarium oxysporum, Thermomyces lanuginosus
Enzyme Microb. Technol.
40
1130-1135
2007
-
2
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
2
-
2
-
2
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
2
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
680300
Lilbaek
Modification of milk and whey ...
Fusarium venenatum
J. Agric. Food Chem.
55
2970-2978
2007
-
2
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
1
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
681568
Vargas-Villarreal
Activity of intracellular phos ...
Giardia intestinalis, Giardia intestinalis IMSS 0989
J. Parasitol.
93
979-984
2007
-
-
-
-
-
-
2
-
3
1
-
-
-
3
-
-
-
-
-
1
-
-
-
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
3
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
682242
Belaunzaran
Phospholipase A1 from Trypanos ...
Trypanosoma cruzi
Parasitology
134
491-502
2007
-
-
-
-
-
-
-
-
3
-
-
1
-
2
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
682933
Santos
Purification, sequencing and s ...
Polybia paulista
Toxicon
50
923-937
2007
-
-
-
-
-
-
-
-
1
-
1
1
-
4
-
-
1
-
-
2
1
-
3
2
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
-
1
-
2
1
-
3
2
1
-
-
-
1
-
-
-
-
-
-
-
-
-
663468
Moawad
Isolation, cloning and charact ...
Polistes dominula
Acta Biol. Hung.
56
261-274
2005
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
664591
Piret
Modulation of the in vitro act ...
Rattus norvegicus
Chem. Phys. Lipids
133
1-15
2005
-
-
-
-
-
-
-
2
1
-
-
-
-
2
-
-
-
-
-
1
3
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
1
3
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
666145
Vargas-Villarreal
Trichomonas vaginalis: identif ...
Trichomonas vaginalis
J. Parasitol.
91
5-11
2005
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
664829
Noiriel
Expression in yeast of a novel ...
Arabidopsis thaliana
Eur. J. Biochem.
271
3752-3764
2004
-
-
-
-
5
-
-
-
1
1
-
-
-
5
-
-
-
-
-
-
-
-
5
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
5
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
666690
Douard
Activity of phospholipases A a ...
Meleagris gallopavo
Poult. Sci.
83
1385-1393
2004
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
666965
Nassogne
Cocaine induces a mixed lysoso ...
Rattus norvegicus
Toxicol. Appl. Pharmacol.
194
101-110
2004
-
1
-
-
-
-
1
-
1
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
650395
Miyazawa
Partial purification and chara ...
Sus scrofa
Biochim. Biophys. Acta
1631
17-25
2003
1
-
-
-
-
-
3
-
1
-
-
1
-
1
-
-
1
-
-
1
1
-
5
-
-
-
-
-
1
1
-
-
-
-
1
1
-
-
-
-
-
-
1
3
-
-
1
-
-
1
-
-
-
1
-
1
1
-
5
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
652486
Hiramatsu
Biochemical and molecular char ...
Homo sapiens
J. Biol. Chem.
278
49438-49447
2003
-
-
1
-
-
-
1
-
1
-
2
1
-
2
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
2
1
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
649376
Song
Construction of DNA-shuffled a ...
Serratia sp.
Appl. Environ. Microbiol.
68
6146-6151
2002
-
-
1
-
1
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
650360
Kingma
Functional importance of calci ...
Escherichia coli
Biochim. Biophys. Acta
1561
230-237
2002
-
-
1
1
6
-
1
-
2
1
2
1
-
1
-
-
1
-
-
-
1
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
6
-
-
1
-
-
2
1
2
1
-
-
-
1
-
-
1
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
650365
oki
Structure and function of phos ...
Rattus norvegicus
Biochim. Biophys. Acta
1582
26-32
2002
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
1
-
-
1
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
652226
Nakajima
A novel phospholipase A1 with ...
Homo sapiens
J. Biol. Chem.
277
11329-11335
2002
-
-
1
-
-
-
-
-
2
-
1
2
-
2
-
-
-
-
-
8
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
2
-
-
-
-
-
8
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
652297
Sonoda
A novel phosphatidic acid-sele ...
Homo sapiens
J. Biol. Chem.
277
34254-34263
2002
-
-
1
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
10
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
10
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
649705
Wainszelbaum
Lysosomal phospholipase A1 in ...
Trypanosoma cruzi
Biochem. J.
355
765-770
2001
1
-
-
-
-
-
1
-
2
-
2
2
-
2
-
1
1
-
-
-
1
-
2
1
-
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
2
-
2
2
-
-
1
1
-
-
1
-
2
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
650631
Shiba
High-level secretory productio ...
Aspergillus oryzae
Biosci. Biotechnol. Biochem.
65
94-101
2001
-
1
1
-
-
-
-
-
-
-
-
1
-
3
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
652153
Hosono
Phosphatidylserine-specific ph ...
Rattus norvegicus
J. Biol. Chem.
276
29664-29670
2001
-
-
1
-
-
-
-
-
-
-
-
1
-
2
-
-
1
-
-
3
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
3
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653458
Ishiguro
The DEFECTIVE IN ANTHER DEHISC ...
Arabidopsis thaliana
Plant Cell
13
2191-2209
2001
-
-
1
-
-
-
-
-
1
-
-
1
-
3
-
-
1
-
-
4
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
1
-
4
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653785
Snijder
Structural investigations of t ...
Escherichia coli
Protein Sci.
10
1962-1969
2001
-
-
1
1
-
-
-
-
2
1
-
1
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
2
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
649360
Song
Simultaneous enhancement of th ...
Serratia sp.
Appl. Environ. Microbiol.
66
890-894
2000
-
-
1
-
1
-
-
1
-
-
-
1
7
1
-
-
1
-
-
-
-
-
2
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
-
-
1
7
-
-
1
-
-
-
-
2
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
649396
Hartmann
Screening for and characteriza ...
Tetrahymena thermophila
Appl. Microbiol. Biotechnol.
54
390-396
2000
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
650008
Lin
Membrane lipids have multiple ...
Bos taurus
Biochemistry
39
9335-9344
2000
-
-
-
-
-
1
-
-
2
-
-
1
-
2
-
-
1
-
-
2
-
-
3
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
1
-
-
-
1
-
2
-
-
3
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
650319
Hirano
Purification and regiospecific ...
Katsuwonus pelamis
Biochim. Biophys. Acta
1483
325-333
2000
-
-
-
-
-
-
-
-
-
-
1
1
-
1
-
-
1
-
-
1
1
-
6
1
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
1
1
-
6
1
1
1
-
-
1
-
-
-
-
-
-
-
-
-
94331
deSilva
Characterization of phospholip ...
Ureaplasma urealyticum
Mol. Cell. Biochem.
201
159-167
1999
-
-
-
-
-
-
-
-
2
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94336
Guberman
A method for the preparation o ...
Tetrahymena thermophila
J. Appl. Microbiol.
86
226-230
1999
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
1
-
-
2
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
2
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
94337
Song
Cloning and expression of the ...
Serratia sp.
J. Biotechnol.
72
103-114
1999
-
-
1
-
-
-
-
-
1
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94340
Uchiyama
Characterization of heparin lo ...
Bos taurus, Mus musculus, Rattus norvegicus
J. Biochem.
125
1001-1010
1999
-
-
-
-
-
-
2
-
-
3
-
-
-
6
-
-
3
-
-
6
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
3
-
-
-
-
-
3
-
6
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94341
Hirano
Properties of phospholipase A1 ...
Katsuwonus pelamis
J. Biochem.
122
1160-1166
1997
-
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
2
-
-
2
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
2
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
94323
Withers-Martinez
A pancreatic lipase with a pho ...
Cavia porcellus
Structure
4
1363-1374
1996
-
-
-
1
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94334
Higgs
Purification and properties of ...
Bos taurus
J. Biol. Chem.
271
10874-10883
1996
1
-
-
-
-
-
1
-
1
-
2
-
-
2
-
-
1
-
-
4
1
-
-
1
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
-
-
1
-
4
1
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94325
Badiani
Evidence for receptor and G-pr ...
Cavia porcellus
Biochem. J.
312
805-809
1995
1
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
94335
Pete
Phospholipid interactions affe ...
Bos taurus
Biochim. Biophys. Acta
1256
367-373
1995
-
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
2
-
-
8
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
8
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
94313
Satouchi
Lysophosphatidylcholine from w ...
Katsuwonus pelamis
Biochim. Biophys. Acta
1214
303-308
1994
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94338
Pete
Purification and properties of ...
Bos taurus
J. Biol. Chem.
269
19494-19500
1994
-
-
-
-
-
-
2
-
-
1
1
-
-
2
-
-
1
-
-
2
1
2
4
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
1
1
-
-
-
-
1
-
2
1
2
4
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
94314
Ueda
A possible pathway of phosphoi ...
Rattus norvegicus
J. Neurochem.
61
1874-1881
1993
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94326
Bellini
Role of a serum phospholipase ...
Bos taurus, Homo sapiens
FEBS Lett.
316
1-4
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
2
-
-
2
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94332
Ueda
The presence of Ca2+-independe ...
Bos taurus
Biochem. Biophys. Res. Commun.
195
1272-1279
1993
-
-
-
-
-
-
-
-
-
1
1
-
-
2
-
-
1
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
1
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94327
Badiani
Evidence for the regulation of ...
Cavia porcellus
Biochem. J.
288
965-968
1992
-
-
-
-
-
-
1
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94328
Sekharam
Plasma membrane-specific phosp ...
Sus scrofa
Toxicol. Appl. Pharmacol.
107
545-554
1991
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94329
Hostetler
Purification of rat kidney lys ...
Rattus norvegicus
Methods Enzymol.
197
325-330
1991
-
-
-
-
-
-
-
-
2
-
1
-
-
2
-
-
1
-
-
2
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
1
-
2
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94333
Scagnelli
Plasma 1-palmitoyl-2-linoleoyl ...
Rattus norvegicus
J. Biol. Chem.
266
18002-18011
1991
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94330
Schmidt
Protease inhibitors reduce lys ...
Rattus norvegicus
Biochem. Int.
20
337-342
1990
-
-
-
-
-
-
1
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94339
Hostetler
Inhibition of kidney lysosomal ...
Rattus norvegicus
J. Pharmacol. Exp. Ther.
254
188-191
1990
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94306
Lffler
Fractionation, biochemical cha ...
Homo sapiens
FEBS Lett.
216
51-56
1987
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
133898
Cao
The purification and character ...
Mesocricetus auratus
J. Biol. Chem.
262
16927-16935
1987
-
-
-
-
-
-
4
1
1
1
2
1
-
1
-
-
1
-
-
1
1
1
7
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
1
1
1
2
1
-
-
-
1
-
1
1
1
7
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94307
Hostetler
Purification of lysosomal phos ...
Rattus norvegicus
Biochemistry
25
6456-6461
1986
-
-
-
-
-
-
1
-
1
1
2
-
-
2
-
1
1
-
-
1
-
-
2
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
1
2
-
-
-
1
1
-
1
-
-
2
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
94308
Nalbone
Partial characterization of ra ...
Rattus norvegicus
Biochim. Biophys. Acta
877
88-95
1986
-
-
-
-
-
-
1
-
2
1
1
-
-
2
-
-
1
-
-
2
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
1
1
-
-
-
-
1
-
2
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
94309
Arai
Properties of acid phospholipa ...
Tetrahymena pyriformis, Tetrahymena pyriformis NT-1
J. Biochem.
99
125-133
1986
-
-
-
-
-
2
2
-
2
-
-
-
-
8
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94310
Flesch
Acylchain specificity and kine ...
Mus musculus
Z. Naturforsch. C
40
356-363
1985
-
-
-
-
-
-
1
1
-
-
-
-
-
2
-
-
-
-
-
4
-
-
4
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
4
-
-
4
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
94303
Fauvel
Substrate specificity of two c ...
Cavia porcellus
Biochim. Biophys. Acta
792
72-78
1984
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
1
8
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94342
Fauvel
Substrate specificity of two c ...
Cavia porcellus
Biochim. Biophys. Acta
792
65-71
1984
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
2
-
-
6
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
6
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94311
Nieder
A phospholipase A1 from the he ...
Manduca sexta
J. Biol. Chem.
258
4304-4310
1983
-
-
-
-
-
-
2
-
-
5
1
-
-
2
-
-
1
-
-
2
1
-
3
-
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
5
1
-
-
-
-
1
-
2
1
-
3
-
1
-
-
-
2
-
-
-
-
-
-
-
-
-
94312
Hostetler
Purification of lysosomal phos ...
Rattus norvegicus
J. Biol. Chem.
257
13367-13373
1982
1
-
-
-
-
-
-
1
-
1
-
-
-
1
-
1
1
-
-
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
1
1
-
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
94304
Fauvel
Purification of two lipases wi ...
Cavia porcellus
Biochim. Biophys. Acta
663
446-456
1981
1
-
-
-
-
-
2
-
-
-
2
-
-
2
-
-
1
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
2
-
-
-
-
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94315
Waite
Phospholipases A1 from lysosom ...
Rattus norvegicus
Methods Enzymol.
71
674-689
1981
-
-
-
-
-
-
2
-
2
1
2
-
-
1
-
-
1
-
-
1
2
-
3
1
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
1
2
-
-
-
-
1
-
1
2
-
3
1
-
-
-
-
2
1
-
-
-
-
-
-
-
-
94316
Bulkacz
Phospholipase A activity in su ...
Prevotella melaninogenica 576, Prevotella melaninogenica
Biochim. Biophys. Acta
664
148-155
1981
-
-
-
-
-
-
-
-
1
1
-
-
-
3
-
-
-
-
-
-
-
-
4
-
1
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
4
-
1
1
1
-
1
-
-
-
-
-
-
-
-
-
94317
Uehara
-
Purification and properties of ...
Corticium centrifugum
Agric. Biol. Chem.
43
517-525
1979
2
-
-
-
-
-
6
-
-
-
1
-
-
1
-
-
1
-
-
-
1
-
1
-
-
-
2
-
1
-
1
-
-
-
-
2
-
-
-
-
-
-
-
6
-
-
-
-
1
-
-
-
-
1
-
-
1
-
1
-
-
-
2
-
1
-
1
-
-
-
-
-
-
-
94318
Krag
Purification and characterizat ...
Bacillus subtilis 168, Bacillus subtilis
J. Biol. Chem.
250
2813-2822
1975
-
-
-
-
-
-
1
-
1
-
-
-
-
90
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94319
Woelk
Distribution and properties of ...
Rattus norvegicus
Hoppe-Seyler's Z. Physiol. Chem.
355
1535-1542
1974
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94320
Nishijima
Purification and properties of ...
Mycolicibacterium phlei
J. Biol. Chem.
249
5658-5667
1974
1
-
-
-
-
-
9
-
1
-
-
-
-
2
-
-
1
-
-
-
1
1
4
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
9
-
-
1
-
-
-
-
-
-
1
-
-
1
1
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
94321
Van den Bosch
Isolation and properties of a ...
Bos taurus
Biochim. Biophys. Acta
348
197-209
1974
1
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
1
-
-
2
1
-
2
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
2
1
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
94322
Woelk
Subcellular distribution and k ...
Rattus norvegicus
Hoppe-Seyler's Z. Physiol. Chem.
354
90-100
1973
-
-
-
-
-
-
2
3
1
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
3
1
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
94324
Scandella
A membrane-bound phospholipase ...
Escherichia coli
Biochemistry
10
4447-4456
1971
-
-
-
-
-
1
1
1
1
1
2
-
-
2
-
-
1
-
-
-
-
-
3
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
1
1
1
2
-
-
-
-
1
-
-
-
-
3
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-