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Literature summary for 3.1.1.31 extracted from

  • Hofer, H.W.; Bauer, H.P.
    6-Phosphogluconolactonase (1987), Cell Biochem. Funct., 5, 97-99.
    View publication on PubMed
Search for more literature for 3.1.1.31

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.83
-
 6-phospho-D-glucono-1,5-lactone synthetic 6-phosphogluconolactone, pH 7.4 Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 native enzyme, gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose
-
 Rattus norvegicus
-
cardiac muscle heart ventricle Rattus norvegicus
-
epididymis
-
 Rattus norvegicus
-
erythrocyte
-
 Bos taurus
-
gastrocnemius
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
soleus
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Saccharomyces cerevisiae
additional information
-
-
 Bos taurus
additional information
-
 specific activity is high in adipose tissue Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-phospho-D-glucono-1,5-lactone + H2O
-
 Rattus norvegicus 6-phospho-D-gluconate
-
 ?
6-phospho-D-glucono-1,5-lactone + H2O
-
 Saccharomyces cerevisiae 6-phospho-D-gluconate
-
 ?
6-phospho-D-glucono-1,5-lactone + H2O
-
 Bos taurus 6-phospho-D-gluconate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 30000, SDS-PAGE Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Bos taurus

pH Range

pH Minimum pH Maximum Comment Organism
5.8 7.5 pH 8, spontaneous hydrolysis drastic increases above Bos taurus